Cancer Stem Cells in Multiple Myeloma

In multiple myeloma "cancer stem" cells can be defined and quantified with flow cytometry. More, these cells can be related to treatment response.

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Key information

Conditions

Multiple Myeloma Blood Protein Disorders Cardiovascular Diseases Hematologic Diseases Hemic and Lymphatic Diseases Hemorrhagic Disorders Hemostatic Disorders Immune System Diseases Immunoproliferative Disorders Lymphoproliferative Disorders Neoplasms Neoplasms by Histologic Type Neoplasms, Plasma Cell Paraproteinemias Vascular Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Ankara University Hematology Unit

Ankara, 06590, Turkey (Türkiye)

About this study

The investigators' hypothesis is that, multiple myeloma plasma cells derivate from principal cells that is called "cancer or progenitor stem cell". In multiple myeloma to define immunophenotyping features of these "cancer stem cells" with flow cytometry and to show their prognostic value and check for any relationship between cancer stem cell quantification and chemotherapy response are main aims of this study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

New Diagnosed or Relapsed Multiple Myeloma
Routine Bone Marrow Aspiration will be done

Exclusion criteria

Bone Marrow Aspiration is not Needed

Treatment and study plan

Primary outcomes

Treatment Response

Time frame: 3 months

After 3 courses chemotherapy treatment response

Secondary outcomes

Treatment Response

Time frame: 6 months

After 6 courses chemotherapy treatment response

Sponsors and collaborators

Lead sponsor

Ankara University

Other

Registry information

Official study title

Flow Cytometric Definition and Prognostic Effects of Multiple Myeloma Cancer Stem Cells

Important dates

Study start: 2013
Primary completion: 2016
Study completion: 2016
First posted: Mar 28, 2013
Registry last updated: Jan 6, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed