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NCT Number: NCT07218614

Can Mobilizations Applied to the Thoracic Spine Improve Oxygen Saturation Levels and Thoracic Kyphosis in E-Cigarette Smokers?

The goal of this study is to determine if manual therapy can improve thoracic spinal posture and pulse oximetery in individuals who use e-cigarettes.

The main questions the study aims to answer are:

* Is there an immediate improvements in thoracic posture * Is there immediate improvements in pulse oximetery Research will compare an experimental group and a control group to examine the effects.

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

All participants will be recruited from flyers posted throughout the NYIT Long Island campus. The participants will be screened for inclusion using set criteria by the PI.

In this crossover design study, participants will be randomly assigned to either an intervention experimental group or sham control group. The intervention group will received a thoracic extension mobilization to the mid-thoracic spine for a duration of 60 seconds and this will be repeated for a total of three times. The sham group will received a light, non-therapeutic touch to both scapulae which will be applied for three minutes. Both interventions will be performed in a seated position. Measurements of thoracic kyphosis and oxygen saturation will be taken before and after each procedure using inclinometers and a pulse oximeter, respectively.

After a washout period of one week, the participants will be return and receive the other form of intervention that they did no receive in in the first week. All procedures and outcomes will be performed as noted above.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Current e-cigarette user Accentuated thoracic kyphosis (Cobb angle >20 degrees) Age range: at least 18 years old Good overall health

Exclusion criteria

History of respiratory disease Recent vertebral fractures Recent spinal surgery Vertebral instability Congenital or acquired thoracic cage deformities Prolonged steroid use Osteoporosis/osteoporosis Inability to provide informed consent

Treatment and study plan

thoracic mobilization

Other

The intervention group will receive a posterior to anterior directed thoracic mobilization to the mid-thoracic spine to facilitate extension. This will be imparted for a duration of 60 seconds, and this will be repeated for a total of three times. Interventions will be performed in a seated position.

Light Touch Contact

Other

The sham treatment will be applied to each subject. The sham treatment of light, non-therapeutic touch will be applied to both scapulae for three minutes. Interventions will be performed in a seated position.

Primary outcomes

  1. Angle of Thoracic Kyphosis

    Time frame: Immediately before and after each intervention

    Measurement of the thoracic kyphosis will be made both pre and post treatment using excepted normative values (Cobb angle)

Secondary outcomes

  1. Oxygen Saturation

    Time frame: immediately before and after intervention

    Percentage of oxygen found in the peripheral circulation using a pulse oximeter

Study contacts

Contact information is provided by the study sponsor or research team.

Mark J Gugliotti, DPT

CONTACT

[email protected]

631-512-5559

Teresa M Ingenito, DPT

CONTACT

[email protected]

516-635-3974

Sponsors and collaborators

Lead sponsor

New York Institute of Technology

Other

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Oct 20, 2025
Registry last updated
Oct 20, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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