Can Fish Oil and Phytochemical Supplements Mimic Anti-Aging Effects of Calorie Restriction?

The purpose of this study is to determine if a combination of 10 nutritional supplements provide health benefits that are consistent with protection against age-related disease. All supplements have been shown in previous studies to have health benefits when administered alone. The hypothesis is that 6 months of taking 10 nutritional supplements each day will provide beneficial changes in healthy related measures.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Healthy Volunteers

Age range

40 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Washington University Medical Center

St Louis, Missouri, 63110, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age 40-60 yr
body mass index of 21 - 30 kg/m2
sedentary to moderately active
eating a typical US diet

Exclusion criteria

history of any chronic disease other than mild osteoarthritis
use of medications other than occasional use of non-steroidal anti-inflammatory drugs, antihistamines, antacids or laxatives
use of nutritional supplements
smoking
alcohol intake greater than two drinks per day for women and three drinks per day for men

Treatment and study plan

Supplement

Dietary Supplement

Participants in this group will take the following nutritional supplements on a daily basis: curcumin, fish oil, resveratrol, sesamin, Acetyl-L-carnitine, lipoic acid, green and black teas, quercetin, pomegranate, cinnamon bark.

Primary outcomes

Carotid-femoral pulse wave velocity

Time frame: Baseline and 6 months

Sponsors and collaborators

Lead sponsor

Washington University School of Medicine

Other

Collaborators

Barnes-Jewish Hospital

Registry information

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Dec 19, 2012
Registry last updated: Dec 19, 2012

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed