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Completed

NCT Number: NCT01815203

Caffein Consumption and Response Inhibition

With the abundance of energy-dense foods that are designed for ease of consumption in the current environment, it is of importance to better understand the factors that may undermine the control of energy intake at healthy levels.

One of the factors that is potentially important in response inhibition is caffeine.

The aim is to assess the direct effects of caffeine on response inhibition, using a No Go/Go-task. We will also assess whether the presentation of food cues, i.e. as words or as pictures, modulate response inhibition different in restrained vs. non-restrained eaters.

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Key information

Conditions

Eating Behavior Behavior Behavior, Animal Body Weight Feeding Behavior Nutrition Disorders Nutritional and Metabolic Diseases Obesity Overnutrition Overweight Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–35 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Uppsala University

Uppsala, 75319, Sweden

About this study

In a blinded, randomized cross-over design, participants will receive either a capsule with caffeine or placebo at two separate occasions whereupon study tasks will be performed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Only males
  • 18 ≤ 35 years
  • Healthy (self rated)
  • Used to drink caffeine
  • Used to eat breakfast regularly (≥ 5 times a week).
  • Non-smokers

Exclusion criteria

  • BMI outside the range of 18,5 ≤ 25
  • hypersensitivity for the ingredients of the foods under study
  • being a vegan or vegetarian. Participants reported not using products that are artificially sweetened, nor sugar in coffee and/or tea
  • Presence of any chronically disease and/or treatment with medication

Treatment and study plan

Caffeine

Drug

Administration of one gelatin capsule containing 200-300 mg of caffeine with subsequent cognitive tasks and food test.

Placebo

Drug

Administration of placebo with subsequent cognitive tasks and food test.

Primary outcomes

  1. Inhibition control

    Time frame: 20 min

    Measurement inhibition control via a computer test (NoGo-Go task.

Secondary outcomes

  1. Food test

    Time frame: 20 min

    Measure of participants food intake.

Other outcomes

  1. Blood sample

    Time frame: 5 min (1 sample)

    Blood glucose assessment in order to confirm fasted condition prior to study experiments.

Sponsors and collaborators

Lead sponsor

Uppsala University

Other

Registry information

Official study title

Does Caffeine Consumption Improve Response Inhibition to Food Cues?

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Mar 20, 2013
Registry last updated
Sep 25, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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