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Completed

NCT Number: NCT07570030

CAF & Firefighters Performance

The aim of the study being to investigate chewing caffeine-containing gum could effectively improve firefighters' balance under conditions of brain fatigue.

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Key information

Conditions

Performance Enhancement

Age range

20 year–40 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

National Taiwan University of Sport

Taichung, North, 404, Taiwan

About this study

14 healthy adult male active-duty firefighters as participants and used a crossover double-blind design, dividing them into a CAF trial and a PL trial. On the first day of the experiment, after the participants had taken sufficient time off and had a full night's sleep, they rested for 3 hours after dinner on the second day. Following the collection of saliva samples, baseline heart rate variability and firefighting ability tests were conducted. After the tests, the participants ingested 800 mg of GABA and rested for 30 minutes. After that, the participants chewed caffeinated gum containing 3 mg/kg (CAF trial) or caffeine-free placebo gum (PL trial) for 10 minutes, spit it out, rested for 15 minutes. The participants underwent eight firefighting balance tests, during which heart rate variability was measured. After the tests were completed, saliva samples were collected again.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Active-duty members of the Special Search and Rescue Brigade
  • Regularly perform firefighting and disaster relief duties
  • Have fully recovered from sports injuries such as strains or sprains for at least 3 months

Exclusion criteria

  • Members who are not part of the Special Search and Rescue Brigade.
  • Individuals who do not regularly perform firefighting and disaster relief duties
  • Participants who have not fully recovered from sports injuries for at least 3 months

Treatment and study plan

Caffeine (300 mg)

Dietary Supplement

The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes.

Placebo

Other

The participants chewing either caffeine Gum (CAF trial, containing 3 mg/kg of caffeine) or Placebo Gum (PL) for 10 minutes.

Primary outcomes

  1. firefighting balance test

    Time frame: 15 minutes after intervention

    Measure the time it takes to return

Sponsors and collaborators

Lead sponsor

Chih-Hui Chiu

Other

Registry information

Official study title

Effects of Caffeinated Chewing Gum on Functional Firefighting Balance Ability After GABA Supplementation

Acronym: CAF & FFT

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
May 6, 2026
Registry last updated
May 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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