CA125 Levels and Other Inflammatory Markers in Laparoscopic Ventral Hernia Repair

The study aims to show variation in CA-125 and other inflammatory markers assumed to be a response to trauma and peritoneal inflammation in the perioperative period of laparoscopic ventral hernia repair

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Key information

Conditions

Hernia Inflammation Pathologic Processes Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Surgical Wound Wounds and Injuries

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Oslo University Hospital, Rikshospitalet, Oslo, Akershus, Norway

About this study

CA-125 and other inflammatory markers as body temperature, CRP, PCT, leucocytes and neutrophils measured pre- and post-operatively - correlated to trauma size i.e. area of dissection, mesh size, number of fixation points etc.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults admitted for ventral or incisional hernia repair

Exclusion criteria

Loss-of-domain
ASA above III
Liver failure
Abnormal CA-125 prior to surgery

Treatment and study plan

Laparoscopic ventral hernia repair

Procedure

Patients operated with laparoscopic repair of ventral or incisional hernia

Primary outcomes

Level of variation in inflammatory markers related to "trauma" impact

Time frame: 6 weeks post surgery

Sponsors and collaborators

Lead sponsor

Oslo University Hospital

Other

Collaborators

Sykehuset Innlandet HF

Registry information

Official study title

Multi-centre Observational Pilot-study for Evaluation of Variation in CA-125 and Other Inflammatory Markers in the Perioperative Period of Laparoscopic Ventral Hernia Repair

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Mar 25, 2011
Registry last updated: Jan 28, 2013

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed