Burn Coverage of Burn by Tilapia Fish Skin

The goal of this experimental study is to compare TFS and regular dressings as coverage for acute thermal burns. The main question it aims to answer is:

Is TFS effective in treating thermal burns? burn induction was done on rabbits to obtain second-degree thermal burn, followed by coverage with TFS

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Key information

Conditions

Tilapia Fish Skin in Burn Coverage

Age range

1 year–18 month

Sex eligibility

Male

Study type

Observational

Primary location

Amira Anter

Aswān, Egypt

About this study

Nile Tilapia Fish Skin (NTFS) has been suggested as an option for biological material for the management of burns. Nile Tilapia Fish Skin also presented a large composition of type I collagen, morphology similar to human skin and high resistance and tensile extension at the break. We chose Baladi rabbits for their relatively ease of handling, accommodation and resistance to surgical aggressions and infectious processes, with low mortality. However, the choice of male rabbits is due to variations in hormonal cycles in females that could intervene in the process of tissue repair.

This experimental model was established to evaluate healing process and outcome results after application of Tilapia Fish Skin on acute contact thermal that was done in order to obtain injuries with the same size and depth.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

healthy male one year old rabbit

Exclusion criteria

female unhealthy rabbits

Treatment and study plan

TFS

Procedure

burn coverage with TFS

Primary outcomes

Tilapia Fish Skin Coverage in Acute Thermal Burn

Time frame: 1 year

Sponsors and collaborators

Lead sponsor

Aswan University

Other

Registry information

Official study title

Tilapia Fish Skin Coverage in Acute Thermal Burn; Experimental and Histopathological Study

Acronym: TFS

Important dates

Study start: 2022
Primary completion: 2024
Study completion: 2024
First posted: Aug 12, 2024
Registry last updated: Aug 12, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.