Skip to main content
OpenTrials
Completed

NCT Number: NCT06292273

Bupivacaine With Dexmedetomidine Versus Bupivacaine Alone for Transversus Abdominis Plane Block in Caesarean Section

Transversus Abdominis plane (TAP) block is a regional technique for providing analgesia of the anterolateral abdominal wall. TAP block are commonly given in patients who have undergone various abdominal as well as pelvic surgeries such as caesarean section, hysterectomy, appendicectomy and various laparoscopic surgeries. this study is conducted to analyse the effect of addition of dexmedetomidine to bupivacaine in Transversus Abdominis Plane (TAP) block.

Completed

Looking for future studies?

Notify Me

Key information

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of Medicine Menoufia University

Cairo, Governorate, 32511, Egypt

About this study

Peripheral nerve block is becoming increasingly popular technique for postoperative pain relief and is also established as a part of multimodal analgesia and enhanced recovery program. Transversus abdominis plane (TAP) block is a regional technique for providing analgesia of the anterolateral abdominal wall. TAP block are commonly given in patients who have undergone various abdominal as well as pelvic surgeries such as caesarean section, hysterectomy, appendicectomy and various laparoscopic surgeries.The Purpose of a TAP block is to infiltrate local anaesthetic agents in the plane between the internal oblique and transversus abdominis muscles thereby providing effective postoperative analgesia. Earlier the blind TAP block (through lumbar triangle of Petit) was commonly given but with widespread use of ultrasound nowadays it is almost always given under ultrasound guidance. Accuracy and efficacy of TAP block is significantly improved under ultrasound guidance because under ultrasound guidance the anesthetic agent can be properly deposited in the neurovascular plane. Ultrasound provides real time and direct visualisation of needle during infiltration of local anaesthetic drug.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • pregnant female elected for cesarean section
  • ASAll

Exclusion criteria

  • coagulopathy
  • BMI>35
  • heart Diseases
  • diabets

Treatment and study plan

Transversus Abdominis Plane Block with bupivacain Plus dexamethasone

Procedure

Bupivacain 0.1%, 35 ml with dexmedetomidine 0.5 µG/kg on each side

Transversus Abdominis Plane Block with bupivacain

Procedure

plain bupivacaine 0.25%, 25 ml bilaterally

Primary outcomes

  1. Post operative pain

    Time frame: 24 hours

    visual analog score from 0 to 10 where 0 is no pain and 10 worst pain ever

Secondary outcomes

  1. Sedation

    Time frame: 24 hours

    Modefied Ramsey sedation score from 1 to 6

  2. Heart rate

    Time frame: 24 hours

    pulse/ min

  3. Total analgesic consumption

    Time frame: 24 hours

    Mg

  4. Side effects

    Time frame: 24hours

    Nausea, vomiting, pruritus

Sponsors and collaborators

Lead sponsor

Menoufia University

Other

Registry information

Official study title

Bupivacaine With Dexmedetomidine Versus Bupivacaine Alone for Transversus Abdominis Plane Block for Post-operative Analgesia in Patients Undergoing Caesarean Section: A Comparative Study.

Important dates

Study start
2023
Primary completion
2024
Study completion
2024
First posted
Mar 5, 2024
Registry last updated
Mar 5, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.