Bronchial Obstruction in Dairy Farmers

Chronic Obstructive Pulmonary Disease (COPD) is a major public health problem and is expected to become the 3rd leading cause of death globally by 2020.

The main risk factor is tobacco. Tobacco poisoning is found in 80 to 90% of patients with COPD. However, non-smoking COPD is also described, with increasing prevalence figures, particularly related to occupational exposure, especially among farmers.

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Key information

Conditions

COPD Chronic Disease Disease Attributes Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Rennes University Hospital - Service de Pneumologie

Rennes, 35033, France

About this study

A prospective screening study based on questionnaires and electronic mini-spirometry (Néo-6®) that includes a representative sample of dairy farmers from the departments of Morbihan and Île-et-Vilaine in Brittany.

The dairy farmers had an occupational medicine appointment and, if they demonstrated at least one marker of possible bronchial obstruction (chronic cough, chronic bronchitis, dyspnoea, wheezing, spirometry), they were referred to a pulmonologist.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

dairy farmers from the departments of Morbihan and Île-et-Vilaine in Brittany
control: non farmer

Exclusion criteria

pigs or grain farmers
Pregnant women
oral corticosteroids or immunosuppressive drugs

Treatment and study plan

questionnaires and electronic mini-spirometry

Other

prospective screening study based on questionnaires and electronic mini-spirometry (Néo-6(®)) that includes a representative sample of dairy farmers from the departments of Morbihan and Île-et-Vilaine in Brittany

Primary outcomes

Level of bronchial obstruction

Time frame: 3 years

Respiratory specific indices are extracted from a screening spirometry :

Forced expiratory volume in one second (FEV1) Forced Vital Capacity (FVC)

Bronchial obstruction is stated with a ratio FEV1 / FVC < 0.8

Secondary outcomes

Prevalence of occupational specific COPD in dairy farmers

Time frame: 3 years
Occupational specific COPD is defined as a ratio FEV1 / FVC < 0.8 associated to a clinical situation :
- non reversibility after β2-agonists or corticoids administration,
- no personal nor familial allergic conditions,
- smoking history < 1 cigarettes package per year.

Sponsors and collaborators

Lead sponsor

Rennes University Hospital

Other

Registry information

Acronym: BPCO Airbag

Important dates

Study start: 2012
Primary completion: 2017
Study completion: 2019
First posted: Aug 31, 2018
Registry last updated: Mar 29, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed