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Completed

NCT Number: NCT02867657

Bringing the Practice of Mindfulness Into Nature - Preventing Mental Fatigue in Healthcare Professionals.

The purpose of the study is to determine whether a five day mindfulness retreat in nature can increase measures of attention and self-compassion, and reduce stress among bachelor students at Danish Universities and University Colleges. Secondary whether the expression of inflammatory markers can be reduced .

It is the hypothesis that perceived stress is reduced and the expression of genetic markers of inflammation is reduced after a five day mindfulness retreat.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

VIA University College, Aarhus, Denmark

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Bachelor student at a Danish University or University College
  • A score of 16 or above on the Perceived Stress Scale (PSS)

Exclusion criteria

  • Smoking
  • Psychiatric diagnosis (depression, anxiety, adjustment disorder, PTSD, personality disorder, psychosis).
  • Untreated ADHD, autism, abuse and risk of suicide

Treatment and study plan

Mindfulness

Behavioral

Five days MBSR curriculum with meditation and yoga

Other names: Mindfulness Based Stress Reduction, MBSR

Primary outcomes

  1. Perceived Stress Scale

    Time frame: At the end of five days retreat

    PSS

  2. Self-compassion

    Time frame: At the end of five days retreat

    S-C-S Neff2

Secondary outcomes

  1. Five Facet Mindfulness Questionnaire

    Time frame: At the end of five days retreat

  2. Breath Counting

    Time frame: At the end of five days retreat

    Behavioral measurement of attention

  3. NF-kB gene expression

    Time frame: At the end of five days retreat

  4. IL-1 gene expression

    Time frame: At the end of five days retreat

  5. IL-6 gene expression

    Time frame: At the end of five days retreat

  6. cRP expression

    Time frame: At the end of five days retreat

    c reactive protein

  7. Heart Rate Variability

    Time frame: At the end of five days retreat

    HRV

  8. Blood pressure

    Time frame: At the end of five days retreat

  9. Connectedness to Nature Scale

    Time frame: At the end of five days retreat

  10. GR gene expression

    Time frame: At the end of five days retreat

  11. RIPK2 gene expression

    Time frame: At the end of five days retreat

  12. TNF-α gene expression

    Time frame: At the end of five days retreat

  13. CCL5 gene expression

    Time frame: At the end of five days retreat

  14. IL-8 gene expression

    Time frame: At the end of five days retreat

  15. TERT gene expression

    Time frame: At the end of five days retreat

  16. TERC gene expression

    Time frame: At the end of five days retreat

  17. IL-1β protein expression

    Time frame: At the end of five days retreat

  18. IL-2 protein expression

    Time frame: At the end of five days retreat

  19. IL-4 protein expression

    Time frame: At the end of five days retreat

  20. IL-6 protein expression

    Time frame: At the end of five days retreat

  21. IL-8 protein expression

    Time frame: At the end of five days retreat

  22. IL-10 protein expression

    Time frame: At the end of five days retreat

  23. IL-12p70 protein expression

    Time frame: At the end of five days retreat

  24. IL-13 protein expression

    Time frame: At the end of five days retreat

  25. TNF-α protein expression

    Time frame: At the end of five days retreat

  26. IFN-γ protein expression

    Time frame: At the end of five days retreat

Sponsors and collaborators

Lead sponsor

VIA University College

Other

Collaborators

  • University of Aarhus
  • University of Copenhagen

Registry information

Official study title

Enhancement of Presence, Compassion and Resilience Bringing the Practice of Mindfulness Into Nature - Preventing Mental Fatigue in Healthcare Professionals.

Important dates

Study start
2016
Primary completion
2018
Study completion
2018
First posted
Aug 16, 2016
Registry last updated
Mar 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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