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NCT Number: NCT07442617

Bridging the Gap Between Prescription and Practice: Impact of Nurse-Led Inhaler Education

Asthma and chronic obstructive pulmonary disease (COPD) are among the most prevalent chronic respiratory conditions worldwide, affecting hundreds of millions of individuals and contributing substantially to morbidity, mortality, and healthcare burden. Although clinicians routinely advise patients verbally on inhaler use, the lack of structured, hands-on education results in significant variation in technique and consistently poor retention of skills over time.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mohamed AbdElmoniem

Al Mansurah, 35516, Egypt

About this study

Asthma and chronic obstructive pulmonary disease (COPD) are among the most prevalent chronic respiratory conditions worldwide, affecting hundreds of millions of individuals and contributing substantially to morbidity, mortality, and healthcare burden. Inhaled therapy remains the cornerstone of management for both diseases, providing targeted delivery of bronchodilators and corticosteroids while minimizing systemic side effects.

Despite correct prescription of inhaler devices, a large proportion of patients demonstrate incorrect technique in inhaler use, leading to suboptimal drug delivery, poor symptom control, increased exacerbations, and frequent emergency department visits. Multiple factors contribute to this gap between prescription and real-world practice, including poor patient understanding of device mechanics, inappropriate inhalation patterns, and misconceptions about the nature and safety of inhaled corticosteroids.

Although clinicians routinely advise patients verbally on inhaler use, the lack of structured, hands-on education results in significant variation in technique and consistently poor retention of skills over time. Nurses, who often maintain the most direct and sustained contact with patients, represent an underutilized resource in addressing this gap. Previous studies indicate that nurse-led inhaler education can significantly enhance practical technique, reinforce adherence, and correct misconceptions about medication use. However, there is limited evidence on the long-term retention of inhaler skills and the impact of structured nurse training on both nurse competency and patient outcomes.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged ≥18 years diagnosed with Asthma or COPD according to GINA / GOLD guidelines
  • Current use of inhaler therapy (MDI, DPI, or Nebulizer) for ≥3 months.
  • Able to understand instructions and perform inhaler technique assessments.
  • Willing to provide informed consent and participate in all study assessments.

Exclusion criteria

  • Acute exacerbation requiring hospitalization at the time of enrollment.
  • Cognitive impairment or neurological disorders preventing understanding or proper inhaler use.
  • Severe comorbidities (e.g., advanced heart failure, end-stage renal disease) that limit participation.

Treatment and study plan

Inhaler technique

Procedure

Patient Education: Conducted by trained nurses using standardized checklist (GINA/GOLD)

Primary outcomes

  1. impact of nurse-led education on inhaler technique

    Time frame: 1 month

    Participants will be evaluated to assess the impact of nurse-led education on technique Score: 152 This score evaluates the patient's ability to correctly use their inhaler. It covers nine key 153 components: ensuring the prescribed device type is used (MDI, DPI, or nebulizer), shaking 154 the MDI before use, complete exhalation before inhalation, proper lip seal around the 155 mouthpiece or spacer, correct inhalation speed according to device type, holding breath after 156 inhalation, rinsing the mouth after corticosteroid sprays, correct use of spacer devices, and 157 overall error correction. The maximum possible score is 9 points. Scores are interpreted as 158 follows: ≥8 indicates excellent technique, 5-7 represents moderate performance, and ≤4 159 indicates poor technique. The checklist was adapted from guideline-recommended inhaler 160 technique steps according to GINA and GOLD reports

Sponsors and collaborators

Lead sponsor

Mansoura University Hospital

Other

Registry information

Official study title

Bridging the Gap Between Prescription and Practice: Impact of Nurse-Led Inhaler Education on Patient Technique, Knowledge, Adherence, and Beliefs - A Randomized Clinical Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 2, 2026
Registry last updated
Mar 2, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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