National Cheng Kung University Hospital
Tainan, 704, Taiwan
NCT Number: NCT04857541
The study will recruit subject of healthy adult, COPD-like patient and patient with COPD to investigate the difference of respiratory performance. We will measure the body composition, respiratory muscle force, pulmonary function and performance of voluntary cough. The muscle thickness of abdominal muscle and diaphragm, assessment of diaphragm during different breathing pattern and the muscle activation during voluntary cough will also being determined. We hypothesized that there will be a significantly different between three group on the performance of voluntary cough, and the correlation between each variable will be further investigated.
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Notify Me20 year and older
All sexes
Observational
Tainan, 704, Taiwan
The specific aims of the study are:
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Inclusion criteria
Inclusion criteria
Exclusion criteria
Time frame: baseline
Peak coughing velocity of voluntary cough in liter/second
Time frame: baseline
MIP/MEP in cmH2O
Time frame: baseline
PEF/MVV in liter/min
Time frame: baseline
FEV1/FVC/VT in liter
Time frame: baseline
MVV rate in breaths/min
Time frame: baseline
tRA/tEO/tIO/tTrA/tD in millimeter
Time frame: baseline
aURA/aLRA/aEO/aIOTrA/aD (all the data will be collected through surface EMG and will be presented as maximal voluntary contraction in %)
Time frame: baseline
QB_ex/DB_ex/Sniff_ex in millimeter
Time frame: baseline
QB_slope/DB_slope/Sniff_slope in cm/s
National Cheng-Kung University Hospital
Other
Investigation of Breathing Performance of Healthy Young Adult
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