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NCT Number: NCT06472167

Breathing Exercises on Lung Function

aim of this study is to evaluate the efficacy of pulmonary rehabilitation program as a non-pharmacological treatment method to: Improve functional capacity as assessed by six-minute walking distance (6MWD) test. Improve dyspnea level as assessed by Medical Research Council (MRC) dyspnea scale. Improve pulmonary function tests and arterial blood gas.

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Key information

Conditions

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Mohamed AbdElmoniem

Al Mansurah, 35516, Egypt

Location status: Recruiting

Location contact

Mohamed AbdElmoniem

CONTACT

[email protected]

01014008473

Mohamed AbdElmoniem, Lecturer

PRINCIPAL_INVESTIGATOR

Mohamed Ahmed Ibrahim

CONTACT

[email protected]

01014008473

Mohamed Ahmed Ibrahim, Lecturer

SUB_INVESTIGATOR

Mohamed Rafat borham, Lecturer

SUB_INVESTIGATOR

About this study

Breathing exercises offer numerous benefits for individuals with chronic airway diseases, such as chronic obstructive pulmonary disease (COPD), asthma and bronchiectasis. These exercises help improve respiratory function, reduce symptoms, and enhance the overall quality of life.Techniques such as diaphragmatic breathing, incentive spirometer and pursed lip breathing help patients use their lungs more effectively. Breathing exercises can enhance lung function by increasing the efficiency of the respiratory muscles and improving ventilation. Asthma is a chronic inflammatory disorder of the airways classified as intermittent or persistent (mild, moderate or severe), according to the presence of diurnal and nocturnal symptoms, necessity of medication, frequency of exacerbation, physical activity limitations and pulmonary function. All of these symptoms deteriorate in the patient's quality of life and psychological well-being and restrict daily living physical activities (DLPA). Asthma symptoms experienced during daily living physical activities (DLPA) or the fear of triggering symptoms may keep asthmatic subjects from engaging in physical exercise, and the patients tend to be less physically active and less conditioned than healthy individuals. In addition, asthmatic patients have higher levels of anxiety and depression that have been shown to be associated with an increased number of exacerbations and the diagnosis of severe asthma. These psychosocial disorders can modify the respiratory breathing pattern, which leads to irregular breathing, frequent sighing, and predominant thoracic breathing. These irregular breathing patterns increase the number of respiratory (breathlessness, chest tightness and pain) and non-respiratory symptoms (anxiety, dizziness and fatigue). Recent Global Initiative for Chronic Obstructive Pulmonary Disease guidelines (GOLD) underline the importance of pulmonary rehabilitation (PR) as a part of an integrative multidisciplinary approach regardless of the stage of disease

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The patients fulfilled the criteria for COPD: the presence of a post bronchodilator FEV1 < 80% predicated together with an FEV1/FVC <0.70confirm the presence of airflow limitation that is not fully reversible.
  • COPD patients ranging from mild to severe according to GOLD [stages I-IV].
  • Asthmatic patients receive medical treatment for at least 6 months; and clinically stable (i.e., no exacerbation or changes in medication for ≥30 days).
  • None of the individuals had been engaged in any exercise-training program before participating in the study.
  • Optimized medical therapy according to GOLD & Global Initiative for Asthma (GINA)
  • Clinically stable COPD and asthmatic patients (not suffering from a recent respiratory tract infection).
  • All patients are Ex-smoker

Exclusion criteria

  • Age <18 years.
  • Pregnancy
  • Current Smokers
  • Patients that are incapable of exercising; unable to understand any questionnaire
  • Multiple co- morbidity (e.g., cardiovascular diseases, active cancer)
  • Neuromuscular disease as Myasthenia gravis, kypho-scoliosis
  • Diaphragmatic Paralysis (paralyzed diaphragm exhibiting abnormal paradoxical movement, i.e., moving in a cranial direction during inspiration).

Treatment and study plan

breathing exercises

Behavioral

Breathing exercises as diaphragmatic breathing exercises and pursued lip breathing and incentive spirometry

Other names: Diaphragmatic Breathing exercise, Pursued lip breathing

Primary outcomes

  1. Impact of breathing exercises on Forced expiratory volume on first second (FEV1) in liter

    Time frame: 6 months

    Effect of Breathing exercises on lung function using spirometry

  2. Impact of breathing exercises on Forced vital capacity (FVC) in liter

    Time frame: 6 months

    Effect of Breathing exercises on lung function using spirometry

Study contacts

Contact information is provided by the study sponsor or research team.

Mohamed AbdElmoniem

CONTACT

[email protected]

01014008473

Mohamed Ahmed Ibrahim

CONTACT

Sponsors and collaborators

Lead sponsor

Mansoura University Hospital

Other

Registry information

Official study title

Impact of Breathing Exercises on Lung Function in Chronic Airway Diseases

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jun 25, 2024
Registry last updated
May 29, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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