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Completed

NCT Number: NCT01428557

BREATHE Registry - I Brazilian Registry of Heart Failure

The purpose of this study is to evaluate the demographic, clinical, prognostics characteristics of 1,200 patients admitted with clinical diagnosis of decompensate heart failure in a group of 60 hospitals representative in different regions.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Hospital do Coracao

São Paulo, 04005-000, Brazil

About this study

Background: Several local registries seek to show an isolated clinical characteristics of patients hospitalized with heart failure (HF) in hospitals and communities in Brazil. Overall, the analysis of these data suggests that there are important differences in etiology, the factors of decompensation, treatment and prognosis of HF patients in different regions.

Objectives: To evaluate the demographic, clinical, prognostics characteristics of 1,200 patients admitted with clinical diagnosis of decompensate heart failure in a group of 60 hospitals representative in different regions. Other specific objectives include describing the in-hospital mortality after admission, to describe the content and the reason for re-admission, to assess adherence to evidence-based guidelines (recommended by guidelines), to measure indicators of quality of care and establish a national registry data to allow for comparison with international records of patients admitted with ADHF.

Methods: Observational cross (record) with longitudinal follow-up where patients admitted to public and private hospitals primarily defined in IC will be studied.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • > 18 years old,
  • Boston Criteria > 7,
  • patients hospitalized > 24 hours.

Exclusion criteria

  • myocardial revascularization during last month,
  • heart failure due to sepsis,
  • acute coronary syndrome with ventricular dysfunction as reason for current hospitalization

Treatment and study plan

Primary outcomes

  1. Total mortality

    Time frame: follow up at 3, 6 and 12 months

Secondary outcomes

  1. Proportion of patients receiving interventions with proven benefit shown by different indicators of quality of care.

    Time frame: follow up at 3, 6 and 12 months

Sponsors and collaborators

Lead sponsor

Hospital do Coracao

Other

Collaborators

  • Brazilian Society of Cardiology

Registry information

Acronym: BREATHE

Important dates

Study start
2011
Primary completion
2019
Study completion
2019
First posted
Sep 5, 2011
Registry last updated
Sep 21, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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