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Completed

NCT Number: NCT01835340

Breath Gas Measurement of Propofol During Anesthesia in Patients With Endourological Procedures

Propofol can be measured continuously in breath gas during anesthesia. This study compares propofol concentration in plasma and breath gas and processed electroencephalographic monitoring (bispectral index) under clinical conditions with patients and total intravenous anesthesia. Target controlled infusion technique is used to deliver adequate propofol concentration in plasma.

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Key information

Conditions

Urological Disease Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Male Urogenital Diseases Urogenital Diseases Urologic Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Dept. of Anesthesiology and Intensive Care

Lübeck, Schleswig-Holstein, 23538, Germany

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years of age
  • Written informed consent
  • Ability and willingness to give written informed consent
  • American Society of Anesthesiologists (ASA) risk score I-II

Exclusion criteria

  • Denial of the patient
  • Patients ASA physical status III- IV
  • Pregnancy
  • Volunteers with history of neurological disease or stroke
  • Volunteers with a history of recreational drug abuse
  • Volunteers with a history of alcohol abuse
  • Known drug allergies
  • History of adverse events during general anesthesia
  • Total intravenous anesthesia not practicable

Treatment and study plan

Drug: Propofol Anesthesia Patients will undergo propofol anesthesia.

Device

Primary outcomes

  1. Exhaled propofol (parts per billion)

    Time frame: Continuous measurement over 40 min during the induction of anesthesia and 30 min during recovery of anesthesia

Sponsors and collaborators

Lead sponsor

University of Luebeck

Other

Collaborators

  • Draeger

Registry information

Official study title

Study to Estimate Central Propofol Effect by Measuring Exhaled Propofol Concentrations in Patients

Important dates

Study start
2012
Primary completion
2017
Study completion
2017
First posted
Apr 18, 2013
Registry last updated
Dec 12, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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