Breast Reconstruction and Body Map : Assessment by Functional MRI (REMASCO)

Patients responding criteria for selection and not objecting to participate in this trial will address a quality of life questionnaire at baseline. Then the study procedures differ depending on which group the patient belongs to.

Immediate breast reconstruction group : Six months after surgery (or six months after the implantation of the definitive prosthesis in case of use of a tissue expander), a postoperative fMRI will be performed and patients will be asked to complete a quality of life form and a satisfaction form.

Secondary breast reconstruction group :

• In the two months preceding the surgery, a preoperative fMRI will be performed.
• Six months after surgery (or six months after the implantation of the definitive prosthesis in case of use of a tissue expander), a postoperative fMRI will be performed and patients will be asked to complete a quality of life form and a satisfaction form.

Inclusion criteria

• Patient with an indication of unilateral total mastectomy with immediate breast reconstruction for initial breast cancer or recurrence, Or patient undergoing a unilateral secondary breast reconstruction
• WHO performance status less than or equal to 2
• Age ≥ 18 years
• For patients of childbearing age, use of an effective contraceptive method for the duration of the study
• Patient having been informed and having signed an informed consent form for the study.

Exclusion criteria

• Patient undergoing a breast reconstruction by exclusive lipomodelling
• Contraindication to MRI : claustrophobia, intra-orbital metallic fragment, pregnancy, cochlear implants, incompatible metallic foreign body such as certain pacemaker and mechanical valves
• Patient with an indication of preoperative radiotherapy or adjuvant chemotherapy according to regional and/or national standards
• History of brain surgery
• History of contralateral breast surgery
• History of prophylactic total mastectomy
• Reconstruction techniques using a mixed procedure (autologous + prosthesis)
• Patient on medication that may alter the BOLD signal in MRI
• Pregnant or breastfeeding women
• Patient under tutorship or guardianship