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NCT Number: NCT05786664

Breast Cancer Survivorship Biorepository

This study collects blood samples as well as clinical and self-report data from stage I-III breast cancer survivors to create a biorepository for future use. The creation of this biorepository will allow for future research into links between individual, molecular, and genomic signatures and cancer outcomes.

Recruiting

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Key information

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

USC / Norris Comprehensive Cancer Center

Los Angeles, California, 90033, United States

Location status: Recruiting

Location contact

Audrey Saghian, MPH

CONTACT

[email protected]

323-865-6086

Bodour Salhia, PhD

PRINCIPAL_INVESTIGATOR

About this study

PRIMARY OBJECTIVE:

I. To create an annotated biorepository with prospectively collected blood samples from breast cancer survivors.

SECONDARY OBJECTIVES:

I. To collect comprehensive data on social determinants of health (e.g., race/ethnicity, acculturation, socioeconomic status, and access to care), environmental exposures (based on zip codes/geocoding), lifestyle (e.g., diet, tobacco use), clinicopathologic characteristics, treatment history, follow-up and current disease status, survivorship-related issues.

II. To establish an efficient process for researchers to utilize the biorepository for breast cancer and survivorship-related studies.

OUTLINE:

Patients complete surveys, undergo collection of blood samples, and review of medical records on study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Women of all racial and ethnic groups 18 years of age or older
  • Women with a diagnosis of invasive breast cancer (stages I-III) within the past 7 years
  • Women who have completed active treatment for breast cancer (surgery, chemotherapy, HER2-directed therapy and radiation)
  • Prior participation on clinical trials is allowed

Exclusion criteria

  • Current receipt of interventional clinical trial participation
  • Stage IV (metastatic) cancer
  • Prior history of recurrence (except recurrence following ductal carcinoma in situ)
  • Inability to give informed consent
  • Unable to speak English, Spanish, Chinese, or Korean

Treatment and study plan

Biospecimen Collection

Procedure

Undergo collection of blood samples

Other names: Biological Sample Collection, Biospecimen Collected, Specimen Collection

Electronic Health Record Review

Other

Review of records

Quality-of-Life Assessment

Other

Complete quality-of-life questionnaires

Other names: Quality of Life Assessment

Survey Administration

Other

Complete surveys

Primary outcomes

  1. Biorepository

    Time frame: 5 years

    Number of biological samples collected and stored (blood)

Study contacts

Contact information is provided by the study sponsor or research team.

Audrey Saghian, MPH

CONTACT

[email protected]

323-865-6086

Sponsors and collaborators

Lead sponsor

University of Southern California

Other

Collaborators

  • National Cancer Institute (NCI)

Registry information

Official study title

A Comprehensive Breast Cancer Survivorship Biorepository

Important dates

Study start
2022
Primary completion
2027
Study completion
2028
First posted
Mar 27, 2023
Registry last updated
May 28, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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