BRAINI-2 Elderly Mild TBI European Study

Inclusion criteria

• BRAINI2-ELDERLY DIAGNOSTIC & PROGNOSTIC:

• Patients ≥65 years of age
• Mild TBI (GCS 13-15 on admission) with indication of brain CT scan in the 12 hours after injury ;
• Blood sample obtained ≤12 h after injury and CT scan preferably ≤6h from blood sample.
• BRAINI2-ELDERLY REFERENCE:

• Non TBI patients ≥65 years of age

Exclusion criteria

• BRAINI2-ELDERLY DIAGNOSTIC & PROGNOSTIC:

• Age below 65 years.
• GCS 3-12 on admission
• Time of injury unknown
• Time to injury exceeding 12 hours
• Primary admission for non-traumatic neurological disorder (e.g., stroke, spontaneous, intracranial hematoma)
• Penetrating head trauma
• Patient with mechanical ventilation from the trauma scene or prehospital management.
• Venipuncture not feasible
• No realization of brain CT-scan
• Subject under judiciary control
• Subject in inclusion period of a drug interventional study
• BRAINI2-ELDERLY REFERENCE:

• Subject in inclusion period of another drug interventional study
• Patients harboring a brain tumor
• Patients that have had a stroke or neurosurgical operation 1 month prior to the inclusion in the study.