Brain SPECT Following Cialis (Tadalafil ) Administration

The study will be an open label one and will include 30 patients who underwent ischemic stroke 3 month to 3 years prior to the study. All patients will undergone a baseline brain SPECT perfusion study. 15 patients will take one dose of 20 mg cialis, and will have a second brain SPECT 24 hours after cialis administration. 15 other patients (age and risk factor matched) will be prescribed 5 mg of cialis once daily for 7 days, and a second SPECT study will be performed 24 hours after the last dose.

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Key information

Conditions

Change in Brain Perfusion

Age range

35 year–80 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Male and female patients in the age range of 35-75 years.

Exclusion criteria

known allergic reaction to TF
Medical contraindication to use TF
Hemorrhagic stroke including intracerebral hemorrhage and subarachnoid hemorrhage
Acute stroke or cardiac ischemic event up to 3 month prior to study.
Other neurological brain diseases including degenerative diseases, multiple sclerosis, brain tumors, post severe brain injury (TBI) and migraine headache.
Sensory aphasia.
Cognitive impairment with disability to sign a consent form.Patients' Assessment

Sponsors and collaborators

Lead sponsor

Wolfson Medical Center

Other Gov

Registry information

Official study title

Brain SPECT Perfusion Imaging Following Cialis (Tadalafil ) Administration in Patients With Vascular Risk Factors

Acronym: CIALIS

Important dates

Study start: 2011
Primary completion: 2012
Study completion: 2012
First posted: Jun 15, 2011
Registry last updated: Feb 9, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.