Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients

In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.

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Key information

Conditions

Chronic Stroke

Sex eligibility

All sexes

Study type

Observational

Primary location

Samsung Medical Center

Seoul, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

more than 3 months post-stroke
ischemic or hemorrhagic stroke
a person who understands the experiment and has a willingness to participate and signs the agreement

Exclusion criteria

User of artificial heartbeat
Patients with claustrophobia
Patients with metal implants
Patients who are contraindicated for other common MRI

Treatment and study plan

Chronic stroke

Other

MRI data acquisition and behavioral test

Primary outcomes

Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score

Time frame: Through study completion, an average of 1 year

Strength of connection is obtained by calculating a correlation coefficient between time courses of both regions in fMRI data.
Correlation coefficient between the FA value of a tract and the Fugl-Meyer Assessment score

Time frame: Through study completion, an average of 1 year

FA value is obtained by assessing a diffusion anisotropy of a specific tract in DTI data.

Sponsors and collaborators

Lead sponsor

Samsung Medical Center

Other

Registry information

Official study title

Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Study About Reorganization and Recovery Mechanism of Brain Neural Network for Chronic Stroke Patients

Important dates

Study start: 2015
Primary completion: 2020
Study completion: 2020
First posted: Jan 8, 2018
Registry last updated: Mar 8, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed