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NCT Number: NCT02179905

Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome

This study is to analyze the relationship between brain structure, the heart rate variability and the serum fatty acid component of the irritable bowel syndrome patients.

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Key information

Conditions

Irritable Bowel Syndrome Colonic Diseases Colonic Diseases, Functional Digestive System Diseases Gastrointestinal Diseases Intestinal Diseases

Age range

20 year–50 year

Sex eligibility

Female

Study type

Observational

Primary location

Shin Kong Wu Ho-Su Memorial Hospital

Taipei, 111, Taiwan

About this study

Several studies showed that the gray matter and white matter of the brain related to the symptoms of irritable bowel syndrome patients.

The investigators study is to analyse the relationship between thickness of cortex of irritable patients, the sympathetic tone and the serum fatty acid component of the irritable bowel syndrome patients. It is to clarify the mechanism of irritable bowel syndrome, whether the symptoms of irritable bowel syndrome are related to the thickness of cortex or inflammation status of the body.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • female
  • between 20 and 50 years old
  • meet Rome III criteria

Exclusion criteria

  • colon and small intestinal disease
  • psychiatric disease patients
  • patients received major surgery in the past 5 years
  • diabetic patients
  • patients with metal implant

Treatment and study plan

Primary outcomes

  1. The relationship between brain structure, heart rate variability and fatty acid of the irritable bowel syndrome patients.

    Time frame: Patients who suffered from IBS for more than 5 years.

Secondary outcomes

  1. The relationship between thickness of brain cortex and the symptoms of irritable bowel syndrome

    Time frame: Patients who suffered from IBS for more than 5 years.

Other outcomes

  1. The relationship between heart rate variability and symptoms of irritable bowel syndrome patients.

    Time frame: Patients who suffered from IBS for more than 5 years.

  2. The relationship between component of fatty acid and symptoms of irritable bowel syndrome patients.

    Time frame: Patients who suffered from IBS for more than 5 years.

Sponsors and collaborators

Lead sponsor

Shin Kong Wu Ho-Su Memorial Hospital

Other

Registry information

Important dates

Study start
2013
Primary completion
2013
Study completion
2013
First posted
Jul 2, 2014
Registry last updated
Jul 2, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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