Rearsh Centre on Aging
Sherbrooke, Quebec, J1H4C4, Canada
NCT Number: NCT04466735
A six month randomized controlled intervention with an exogenous ketone salt (EKS) supplement in mild cognitive impairment. Participants will receive 15 g of the supplement twice daily (equivalent to 24 g/day of EKS). Outcomes: brain energy metabolism, cognition, plasma biomarkers, brain imaging (volumetric, functional, structural) and quality of life will be analyzed before and after the intervention.
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Notify Me55 year–80 year
All sexes
Interventional
Not applicable
Sherbrooke, Quebec, J1H4C4, Canada
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
2 x 12 g of EKS/day
Isocaloric placebo supplement with similar salt load but no EKS
Time frame: 6 months
CMRacac measured by PET Scan
Time frame: 6 months
CMRgluc measured by PET Scan
Time frame: 0-3-6-9 months
Time frame: 9 months
glucose, fatty acids, ketones
Time frame: 6 months
Université de Sherbrooke
Other
6 Month Randomized Controlled Trial With D-beta-hydroxybutyrate in Mild Cognitive Impairment
Acronym: BREAK-AD
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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