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Completed

NCT Number: NCT03403257

Brain Attack Surveillance in Corpus Christi--Cognitive (BASIC-Cognitive)

The Mexican American population in the U.S. is rapidly growing and aging. This project seeks to determine the prevalence and outcomes of cognitive impairment and dementia in Mexican Americans. It also seeks solutions to help patients with cognitive impairment and dementia and their caregivers get the resources they need.

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Key information

About this study

Hispanic/Latinos will comprise more than 30% of the U.S. population by mid-century, and Mexican Americans account for the largest share of this growing segment of society. This proposal aims to use door-to-door surveillance in Nueces County, Texas, a non-immigrant, bi-ethnic community, to determine the prevalence and trajectory over time of cognitive impairment and dementia in Mexican Americans and non Hispanic whites. The study will elucidate the mechanisms that explain the hypothesized ethnic disparity in Alzheimer's disease and Alzheimer-related dementias by evaluating the roles of vascular disease risk factors, educational attainment and socio-economic status among others. This research will also delve deeply into the differences in informal caregiving for Mexican American and non Hispanic whites with cognitive impairment and dementia. Caregiver burden and mental and physical health of caregivers will be examined toward efforts to develop interventions that build resilience in caregivers. A novel ability of this population-based study is to examine community resources for both patients and caregivers, and how these provisions differ by ethnicity. Using a rigorous mixed methods approach the study will identify the gap between available resources and needs for those with cognitive impairment and dementia. In this way we will be well positioned to propose ethnic-specific testable interventions that promote mental and physical health for those with cognitive impairment and dementia, as well as for those family members who provide the care. This research will therefore lead to improved well-being, autonomy and outcomes among those with cognitive impairment and dementia and their caregivers. The investigative team members have conducted research in this community for 20 years and are experts in Mexican American culture and health, cognitive impairment and dementia, epidemiologic methods, community needs assessment and health behavior research. As the Mexican American population continues its tremendous growth and aging it is vitally important to better understand the prevalence and outcomes of cognitive impairment and dementia in this population, and to rapidly develop interventions that address the burden of these common conditions in Mexican American adults, families, and communities.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

1.65 years of age or older 2. MoCA < 26 3. Nueces County resident at least 6 months a year 4. English or Spanish speaking 5. Community dwelling or nursing home

Exclusion criteria

none

Treatment and study plan

No interventions

Other

No intervention

Primary outcomes

  1. Prevalence of mild cognitive impairment and dementia in Mexican Americans and non Hispanic whites

    Time frame: 2 year data collection

    Prevalence estimates

  2. Trajectory of cognitive function in Mexican Americans and non Hispanic whites

    Time frame: 2 year follow-up after baseline

    Change in cognitive function among subjects entered at baseline

  3. Caregiver outcomes and changes over time

    Time frame: 4 years

    Comparative caregiver outcomes among Mexican Americans and non Hispanic whites

Secondary outcomes

  1. Needs and community available resources for cognitive impairment

    Time frame: 2 years

    An asset map and determination of needs

Sponsors and collaborators

Lead sponsor

University of Michigan

Other

Collaborators

  • National Institutes of Health (NIH)

Registry information

Acronym: BASIC-C

Important dates

Study start
2018
Primary completion
2026
Study completion
2026
First posted
Jan 18, 2018
Registry last updated
May 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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