brachial plexus tumors excision
Procedureexcision of brachial plexus tumors
NCT Number: NCT07005869
Brachial plexus tumors, are rare, present significant challenges due to their intricate anatomical location and potential impact on upper limb function. These tumors arise from nerve sheath cells, including either benign schwannomas and neurofibromas, or as malignant peripheral nerve sheath tumors (MPNSTs), which require early diagnosis and intervention to improve patient outcomes (1). Surgical resection remains the primary treatment modality, aiming to alleviate symptoms and prevent further neurological compromise.
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Interventional
Not applicable
Brachial plexus tumors, are rare, present significant challenges due to their intricate anatomical location and potential impact on upper limb function. These tumors arise from nerve sheath cells, including either benign schwannomas and neurofibromas, or as malignant peripheral nerve sheath tumors (MPNSTs), which require early diagnosis and intervention to improve patient outcomes (1). Surgical resection remains the primary treatment modality, aiming to alleviate symptoms and prevent further neurological compromise.
The choice of surgical approach is influenced by the tumor's size, location, and relationship with surrounding neurovascular structures. Anterior approaches, including supraclavicular and infraclavicular incisions, provide excellent exposure for lesions in the upper and middle parts of the plexus, whereas posterior approaches are preferred for deep-seated or retroclavicular tumors (2). Intraoperative neurophysiological monitoring (IONM) has significantly improved surgical precision, reducing the risk of postoperative deficit .
Advancements in microsurgical techniques, such as nerve grafting and nerve transfers, have improved functional recovery in patients undergoing brachial plexus tumor resection. Early intervention and meticulous dissection help preserve nerve function and minimize postoperative deficits (3). Minimally invasive techniques, including endoscopic and robotic-assisted approaches, are being explored to reduce morbidity and improve surgical precision (4).
Despite progress in surgical management, challenges remain, particularly in cases of malignant tumors where complete resection may not be feasible. Adjuvant therapies, including radiation and chemotherapy, are increasingly utilized for malignant brachial plexus tumors to enhance local control and reduce recurrence rates (5). Long-term follow-up and rehabilitation play a crucial role in optimizing functional recovery, emphasizing the need for a multidisciplinary approach (6).
This review aims to analyze the indications, techniques, and outcomes of different surgical approaches for brachial plexus tumors, providing insights into optimizing patient outcomes while minimizing surgical morbidity.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
.Patients diagnosed with brachial plexus tumors confirmed through imaging
.Age of Patients: Any age .
.patients who are fit for surgery .
Exclusion criteria
. Patients with non-tumorous brachial plexus pathologies (e.g., trauma, inflammation).
.Patients with incomplete medical records or lost follow-up data.
.Patients with recurrent tumors previously treated.
.Patients who are unfit for surgery.
excision of brachial plexus tumors
Time frame: 2 years
Clinical:
Better outcome according to MRC Muscle Power Scale and Numeric Sensory Scale (NSS) The Medical Research Council (MRC) Muscle Power Scale is commonly used to assess motor power in patients. It ranges from 0 to 5, evaluating voluntary muscle contraction against gravity and resistance.
The Numeric Sensory Scale (NSS) is a simple and effective tool used to assess sensory function.
It is based on a numerical rating system from 0 to 10, where patients self-report their level of sensation. This scale is commonly used in neurological examinations to evaluate sensory deficits.
Time frame: 2 years
Radiological :
Postoperative MRI to detect the residual or recurrence of lesions
Contact information is provided by the study sponsor or research team.
Assiut University
Other
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