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Completed

NCT Number: NCT07296640

BPIT 5-Line Pilot: Interventional Study on Strength, HRV & Injury Risk Reduction (n=23)

This prospective, single-center, interventional pilot (n=23) evaluates the 5-Line Principle of Balanced Intensity Training (BPIT) over 6 weeks at GFFI Fitness Academy. Participants (18 males aged 22-48, 5 females aged 20-33) will receive BPIT 5-Line Training (3 sessions/week, 6 weeks). No control group. Conducted July 1 - November 30, 2024.

Progressive intensity via anatomical lines: 1. Ground-Based (Low Intensity); 2. Knee-Level (Low-Moderate); 3. Standing (Moderate); 4. Head-Level (Moderate-High); 5. Plyometric/High-Impact (High). Aims to assess changes in strength, HRV, and injury risk.

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Key information

Conditions

Healthy

Age range

22 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

GFFI Fitness Academy

New Delhi, National Capital Territory of Delhi, 110026, India

About this study

STUDY DESIGN: Prospective, single-center, interventional pilot (n=23) with single-group assignment. All participants receive the BPIT 5-Line intervention. Assessments at baseline and Week 6.

INTERVENTION: BPIT 5-Line Training: 3 x 60-minute sessions/week for 6 weeks, progressing across five intensity lines: 1. Ground-Based (Low Intensity, e.g., prone planks); 2. Knee-Level (Low-Moderate, e.g., shoulder press); 3. Standing (Moderate, e.g., half-squat); 4. Head-Level (Moderate-High); 5. Plyometric/High-Impact (High Intensity). Specific exercises detailed in Training Protocol Manual.

OBJECTIVES: Primary - Evaluate BPIT's impact on 1RM strength (e.g., squat, bench press, deadlift) and training-related injury incidence. Secondary - Assess changes in HRV (RMSSD), HRR (bpm in 60s), EMG muscle activation, joint biomechanics (knee valgus, spinal curvature), adherence (% sessions completed), and participant feedback (questionnaires).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy adults aged 22-65 years
  • Regular fitness trainees (≥2 sessions/week prior)
  • Able to provide informed consent
  • No recent musculoskeletal injury (past 3 months)

Exclusion criteria

  • - Cardiovascular disease or uncontrolled hypertension
  • Current musculoskeletal injury or surgery (past 6 months)
  • Neurological disorders affecting movement
  • Pregnancy
  • Use of performance-enhancing substances

Treatment and study plan

BPIT 5-Line Training

Behavioral

All 23 participants received BPIT 5-Line Training (3-5 sessions/week, 6 weeks). Intensity progressed via 5 anatomical lines: 1. Ground-Based, Low Intensity; 2. Knee-Level, Low-Moderate; 3. Standing, Moderate; 4. Head-Level, Moderate-High; 5. Plyometric/High-Impact, High Intensity. Sessions 45-60 min, monitored via HRV, pain, fatigue.

Primary outcomes

  1. Change in 1RM Strength

    Time frame: 6 weeks

    Change in one-repetition maximum (1RM) strength for key exercises (e.g., squat, bench press) from baseline to week 6. Measured in kilograms (kg) using standard 1RM testing protocol.

    Time Frame: Baseline to Week 6 Unit of Measure: kilograms (kg)

  2. Injury Incidence

    Time frame: Baseline to Week 6

    Number of new musculoskeletal injuries reported during the study period, defined as any complaint requiring medical attention, training modification, or rest exceeding 1 day. Measured as incidence rate per 100 participant-weeks (normalized for exposure in this 23-participant pilot).

    Unit of Measure: injuries per 100 participant-weeks

Secondary outcomes

  1. Change in Heart Rate Variability (HRV)

    Time frame: Week 6

    Change in Heart Rate Variability (RMSSD) from baseline to week 6, measured via 60-second daily monitoring using HRV device/app.

    Time Frame: Baseline to Week 6 Unit of Measure: milliseconds (ms)

  2. Change in Muscle Activation (EMG Amplitude)

    Time frame: Baseline to Week 6

    Change in Electromyography (EMG) amplitude for key muscle groups during specific exercises from baseline to week 6, measured as percentage of maximum voluntary contraction (%MVC) using EMG equipment.

    Time Frame: Baseline to Week 6 Unit of Measure: percentage of maximum voluntary contraction (%MVC)

  3. Change in Joint Biomechanics (Knee Valgus and Spinal Curvature)

    Time frame: Baseline to Week 6

    Change in knee valgus and spinal curvature angles during functional movements from baseline to week 6, measured in degrees via 3D motion analysis or goniometer.

    Time Frame: Baseline to Week 6 Unit of Measure: degrees

  4. Training Adherence

    Time frame: Baseline to Week 6

    Percentage of completed training sessions from baseline to week 6, measured via session logs.

    Time Frame: Baseline to Week 6 Unit of Measure: percentage

  5. Participant Feedback

    Time frame: 6 weeks

    Qualitative feedback from post-study questionnaires, scored on a Likert scale (1-5) for satisfaction and perceived benefit.

    Time Frame: Week 6 Unit of Measure: units on a scale (1-5)

  6. Heart Rate Recovery (HRR)

    Time frame: 6 Weeks

    Change in Heart Rate Recovery (bpm decrease in 60 seconds post-exercise) from baseline to week 6, measured via HR monitor.

    Time Frame: Baseline to Week 6 Unit of Measure: beats per minute (bpm)

Sponsors and collaborators

Lead sponsor

MMSx Authority Institute for Movement Mechanics & Biomechanics Research Inc.

Other

Registry information

Official study title

A Prospective, Single-Center, Interventional Study to Evaluate the 5-Line Principle of Balanced Intensity Training (BPIT) for Enhancing Physical Performance and Reducing Injury Risk

Acronym: BPIT 5-Line

Important dates

Study start
2024
Primary completion
2024
Study completion
2024
First posted
Dec 22, 2025
Registry last updated
Dec 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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