University of Manitoba
Winnipeg, Manitoba, H2X 1R9, Canada
Location status: Recruiting
NCT Number: NCT06298461
The purpose of this study is to compare how effective and how tolerable two different bowel preparation laxatives are for colonoscopy. The aim is to compare oral sulfate solution (OSS) to another laxative called 2L polyethylene glycol (PEG) solution to see which is more effective and more tolerable by individuals with IBD (Crohn's disease or Ulcerative colitis).
Interested in participating?
Request Info18 year and older
All sexes
Interventional
Phase 4
Winnipeg, Manitoba, H2X 1R9, Canada
Location status: Recruiting
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Laxative for colonoscopy bowel preparation
Laxative for colonoscopy bowel preparation
Time frame: 1 year
The primary outcome will be adequate quality of bowel cleanliness. Proportion with adequate cleansing will be measured by Boston Bowel Preparation Scale Score ≥2 in all segments.
Time frame: 1 year
The primary outcome will be adequate quality of bowel cleanliness. Proportion with adequate cleansing will be measured by the Ottawa scale score as a binary adequate/inadequate score (≤7) will be recorded.
Time frame: 1 year
Will compare completion of laxative intake.
Time frame: 1 year
Will compare dysplasia detection rate.
Time frame: 1 year
Will compare withdrawal time.
Time frame: 1 year
Will compare total procedure time.
Time frame: 1 year
Will compare cecal intubation rate
Time frame: 1 year
Will determine the proportion of patients in each group reporting: use of split dose and day before bowel preparation (even though they were prescribed split-dose) , incontinence episodes during bowel preparation and during travel to the colonoscopy appointment; total duration of sleep; number of nocturnal awakenings: patient willingness to repeat colonoscopy using the same preparation; pre-colonoscopy anxiety rating; difficulty with bowel preparation rating. The study specific patient questionnaire will be administered prior to the colonoscopy to avoid any contamination by the experience of the colonoscopy.
Time frame: One month
A one month phone call to determine diagnosed flares within a month
Time frame: 1 year
Will also compare the proportion of patients requiring repeat colonoscopy because of an inadequate bowel preparation. Will collect data on mucosal abnormality suspected by endoscopist to be due to bowel preparation.
Contact information is provided by the study sponsor or research team.
University of Manitoba
Other
Bowel Preparation for Colonoscopy Among Individuals With IBD: A Randomized Controlled Trial
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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