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OpenTrials
Completed

NCT Number: NCT03580031

Booster Dose of HCG for Unruptured Follicle in Non IVF/ICSI Cycles

This study will be conducted to assess the effect of booster dose of hCG on the unruptured follicles in non IVF/ICSI cycles.

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Key information

Conditions

LUF - Luteinised Unruptured Follicle Syndrome

Age range

20 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Phase 4

Primary location

Ayman Shehata Dawood

Tanta, Algharbia, 31111, Egypt

About this study

In this study enrolled patients (n=160) who underwent controlled ovarian stimulation and timed intercourse with unruptured mature graffian follicle 48 hours after IM 10,000 IU HCG dose. Patients were allocated randomly into intervention group and control group. In the intervention group another booster dose (10,000 IU of hCG) was given IM while in the control group 2 ml normal saline was given IM leaving follicles for spontaneous rupture

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Ordinary stimulated cycles
  • IUI stimulated cycles
  • Unruptured follicle after 10000 IU IM HCG triggering

Exclusion criteria

  • IVF/ICSI cycles

Treatment and study plan

HCG

Drug

A booster dose (10,000 IU of hCG) was given IM 48 hours after first triggering dose

Saline Solution

Drug

2 ml of normal saline will be injected 48 hours after first triggering dose

Primary outcomes

  1. Ovulation rate

    Time frame: 48 hours

    rupture of dominant follicle manifested by disappearance of follicle and presence of free fluid in douglas pouch

Secondary outcomes

  1. Pregnancy rate

    Time frame: 15 days

    Number of cases with positive serum pregnancy test

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Booster Dose of Human Chorionic Gonadotrophin for Unruptured Follicle in Non IVF/ICSI Cycles: A Randomized Controlled Study

Important dates

Study start
2018
Primary completion
2021
Study completion
2021
First posted
Jul 9, 2018
Registry last updated
Feb 21, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.