Bone Status and Insulin Resistance in Hirsutism

The purpose of this study is to investigate how the bones of hirsute women are different from bones of healthy women. The change in hormone content in the blood will also be investigated. The study can be used to evaluate whether it will be relevant to bone scan all newly referred hirsute women.

Hirsute women are often over-weight and often have an increased amount of the male sex hormone in their blood. Their blood tests often show changes reminding of the ones seen in diabetic patients.

All hirsute women referred to the department will undergo an investigation revealing the reason for the increased hair growth. The investigation includes clinical investigation (height, weight and degree of hair growth), blood tests (for hormone status and bone status analysis) and bone scanning of the abdomen (body composition).

The trial includes a group of 50 strongly hairy women and a control group of 50 healthy women with normal hair growth. They are matched by body weight, since weight has great importance for the bone mineral content and thereby for osteoporosis in the long run.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Hirsutism Glucose Metabolism Disorders Hair Diseases Hyperinsulinism Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases Pathological Conditions, Signs and Symptoms Signs and Symptoms Skin Diseases Skin and Connective Tissue Diseases Virilism

Age range

20 year–46 year

Sex eligibility

Female

Study type

Observational

Primary location

Diabetes Research Center

Odense, Funen, 5000, Denmark

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Hirsute subjects:

Belonging to group 1 or 2.
Age: 20-46
Hirsute score: >7
Written informed consent

Control group:

Age: 20-46
Hirsute score: 0 (without razing)
Regular menses
Written informed consent

Exclusion criteria

Previous cosmetic treatment for hirsutism.
Use of contraceptive pill (within the past 6 months)
Systemic steroid treatment > 6 weeks (ever)
Age above 46 years/post menopause (increased FSH)
Recognized diabetes mellitus or other endocrine disease
Eating disorder
Serious, treatment demanding disease

Sponsors and collaborators

Lead sponsor

Odense University Hospital

Other

Registry information

Official study title

Body Composition, Insulin Concentration, Androgens and Bone Status in Women Referred With Hirsutism

Important dates

Study start: 2002
Primary completion: 2007
Study completion: 2007
First posted: Sep 2, 2005
Registry last updated: Jun 24, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed