Skip to main content
OpenTrials
Completed

NCT Number: NCT00363324

Bone Marrow Cells in Myocardial Infarction

This study is aimed to assess the effect of bone marrow cells on arrhythmia risk variables in patients with a acute myocardial infarction.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Acute Myocardial Infarction

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2 / Phase 3

Primary location

University of Oulu

Oulu, 90220, Finland

About this study

This is a randomized, double-blinded study, where patients treated with thrombolytic therapy for acute myocardial infarction are randomized to receive bone-marrow derived stem cells or sham-infusion at the time percutaneous coronary intervention of the target vessel. The end-points are many arrhythmia risk variables, suchs as heart rate variability, T-wave alternans and many ECG variables as well as systolic and diastolic left ventricular function.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Acute ST-elevation myocardial infarction treated with thrombolytic therapy

Exclusion criteria

  • Indication for rescue PCI, severe clinical heart failure, age <18 years

Treatment and study plan

intracoronary injection of bone marrow cells

Procedure

Primary outcomes

  1. Arrhythmia risk variables

  2. left ventricular function

  3. restenosis assessed by IVUS

Secondary outcomes

  1. exercise tolerance

Sponsors and collaborators

Lead sponsor

University of Oulu

Other

Registry information

Official study title

Effects of Autologous Bone Marrow Celss on Acute ST-Elevation Myocardial Infarction

Important dates

Study start
2005
Primary completion
2007
Study completion
2007
First posted
Aug 15, 2006
Registry last updated
Jan 9, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.