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OpenTrials
Completed

NCT Number: NCT00540267

Bone Density in Patients With Schizophrenia

People with chronic mental disorder such as schizophrenia and alcohol abuse are high risk groups for developing osteoporosis.

To evaluate the prevalence of bone mineral density in men patients with schizophrenia with alcohol abuse, the investigators will compare bone mineral density between patient with schizophrenia with and without alcohol abuse.

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Key information

Conditions

Schizophrenia Alcohol Abuse Alcohol-Related Disorders Alcoholism Chemically-Induced Disorders Mental Disorders Schizophrenia Spectrum and Other Psychotic Disorders Substance-Related Disorders

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Joo-Cheol Shim

Busan, 614-735, South Korea

About this study

People with schizophrenia has been known as a high risk groups for developing osteoporosis, because of lack of exercise, poor nutrition and high rate of smoking. Those with alcohol abuse may be higher risk group than one with schizophrenia without alcohol abuse, because they frequently have several medical problems such as liver dysfunction, Vitamin D deficiency, hyperparathyroidism and those medical condition increase risk for developing osteoporosis. Also alcohol itself can increase bone loss too by disturbing bone remodeling and enhancing bone fragility. To compare the prevalence of bone mineral density in patients with schizophrenia with alcohol abuse to those without alcohol problem, we will investigate BMD in large population of Korean patients with those illnesses.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • DSM-IV diagnosis of schizophrenia
  • Onset of illness more than 5 years.

Exclusion criteria

  • No severe Medical and endocrinological disorder

Treatment and study plan

No intervention

Other

No Intervention

Primary outcomes

  1. The change of bone mineral density

    Time frame: cross sectional and prospective

Secondary outcomes

  1. The effects of Smoking and antipsychotic drug on BMD

    Time frame: Cross sectional Study

Sponsors and collaborators

Lead sponsor

Inje University

Other

Registry information

Official study title

Bone Mineral Density in the Korean Patients With Chronic Schizophrenia With Alcohol Abuse

Important dates

Study start
2007
Primary completion
2008
Study completion
2008
First posted
Oct 5, 2007
Registry last updated
Nov 4, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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