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NCT Number: NCT06434441

Bone Augmentation Using Calvarial Versus Iliac Crest Bone Blocks.

This study aims to evaluate and compare the quantity of the radiographic horizontal bone gain of severely deficient complete maxillary ridges reconstructed by bone block harvest from the iliac crest versus the calvarial bones

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Key information

Conditions

Age range

20 year–55 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

About this study

Although the calvarial bones represent a nearby donor site for maxillary augmentation of matching bone origin, the excessive volume of bone needed to reconstruct a severely deficient arch, the limited cancellous bone volume, and the arciform pattern of the skull cap that yield the curvatures of the harvested cortical blocks incompatible with the topography of the maxillary arch, all represent limitations for the calvarial graft.

The anterior iliac crest is frequently used for free bone grafting by being subcutaneous and generous to afford ample bone blocks of favorable curvatures. However, the minute cortical overlay and its endochondral origin contribute to excessive graft resorption. Pikos et al. demonstrated that a reasonable amount of graft resorption could occur with atraumatic surgical intervention and intimate graft fixation.

This study aims to evaluate and compare the quantity of the radiographic horizontal bone gain of severely deficient complete maxillary ridges reconstructed by bone block harvest from the iliac crest versus the calvarial bones.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with the clinical and radiographic interpretation of horizontal maxillary ridge deficiency of less than 5 mm

Exclusion criteria

  • Any previous maxillary reconstructive or dental implant treatment.
  • Any local pathologic lesion or systemic disease that would affect the typical pattern of bone healing.

Treatment and study plan

Autogenous bone augmentation

Procedure

Maxillary alveolar bone reconstruction

Primary outcomes

  1. Horizontal bone gain

    Time frame: 6 months consolidation period

    the study compares the horizontal bone gain of reconstructed maxillary alveolar ridges after being augmented with calverial and iliac crest bone grafts radiographically by millimeters

Secondary outcomes

  1. Immunohistochemical bone formation

    Time frame: 6 months consolidation period

    the study compares the bone area percent of the consolidated calverial and iliac crest bone grafts

Study contacts

Contact information is provided by the study sponsor or research team.

Amr Gibaly

CONTACT

[email protected]

01113336634

Sponsors and collaborators

Lead sponsor

Beni-Suef University

Other

Registry information

Official study title

Radiographic Assessment of Horizontal Bone Augmentation of Full Atrophic Maxillary Alveolar Ridges Using Calvarial Versus Iliac Crest Bone Blocks:

Important dates

Study start
2023
Primary completion
2025
Study completion
2025
First posted
May 30, 2024
Registry last updated
Jan 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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