Bone Augmentation Techniques in Extraction Sockets

The amniotic allograft is a cryopreserved allograft tissue matrix derived from human placental tissues recovered from live healthy donors. Amniotic tissue is an abundant source of collagen which provides an extracellular matrix to act as a natural scaffold for cellular attachment in the body; collagen provides a structural tissue matrix that facilitates cellular migration and proliferation in-vivo. The product is developed using proprietory techniques by BioDlogics, LLC. The amniotic allograft growth factors are thought to enhance formation of a supportive scaffold for regeneration, to facilitate interactions between cell types, and to influence anti-inflammatory, anti-microbial and immuno-privilege activities.

Atraumatic extractions and socket grafts will be performed. Dental implants will be inserted into the grafted areas 8 weeks post-graft. The implants will be restored and followed for 24 months post-insertion.

Inclusion criteria

• Be a registered University of Alabama at Birmingham (UAB) dental school patient
• Existence of one or more non-adjacent teeth in the aesthetic zone that are scheduled for extraction
• Healthy enough to undergo the proposed therapy
• Demonstrated willingness to comply with study directions and time-line
• Able to consent for themselves
• Able to read and understand the informed consent form -

Exclusion criteria

• Pregnant or lactating at the time of enrollment
• Previous Malignant neoplasm
• Known hypersensitivity to bone grafting materials
• Know hypersensitivity to titanium
• Any medical of medication that in the opinion of the investigators may adversely affect bone healing
• Any indication of an inability to make autonomous decisions -