Bonds Between Circulating Tumoral ADN (ctDNA) and the Development of Peritoneal Carcinomatosis for Patients Under PIPAC

Inclusion criteria

• Age ≥ 18 years old
• WHO 0 to 2
• Patient with cancer in the form of peritoneal carcinosmatois not eligible for cytoreduction surgery
• A histological diagnosis of the primary tumor or peritoneal carcinomatosis is essential.
• Patient with an indication for PIPAC for any reason (whether as part of a clinical research protocol or not). Patients with prior treatment with PIPAC are eligible.
• Patients with abdominal metastases or a single metastasis regardless of location (oligometastasis).
• For patients of childbearing age need for an effective method of contraception
• Informing patients and obtaining informed consent, dated and signed.
• Patient affiliated with a social security scheme

Exclusion criteria

• Age < 18 years old
• WHO > 3
• Patient who may benefit from cytoreduction surgery
• Patient with a contraindication to PIPAC
• Extra peritoneal disease with the exception of oligometastatic disease
• Persons deprived of liberty or under guardianship (including curatorship)
• Impossibility to undergo the medical follow-up of the trial for social, geographical or psychological reasons.
• For patients of childbearing age without an effective method of contraception
• Woman who is pregnant, likely to be pregnant, or breastfeeding