Body Temperature in Persons With Tetraplegia When Exposed to Heat

After a cervical spinal cord injury (SCI) the motor, sensory and autonomic deficits cause, among other detriments, a blunted ability to maintain a constant core temperature. Impaired thermoregulation leaves persons with tetraplegia more susceptible to hyperthermia than able-bodied persons (AB). There has been a paucity of work addressing the thermoregulatory responses of persons with SCI to hot ambient temperatures, and even less study addressing the effect of these temperatures on cognitive performance. The goals of this pilot study are: to improve our understanding of the thermoregulatory mechanisms of individuals with tetraplegia when exposed to heat and to determine the effect of impaired thermoregulatory mechanisms on cognitive performance during exposure to 35°C for up to 2 hours. In order to address our goals we have designed a study methodology which consists of comparing the physiological and psychological responses of the two study groups (tetraplegia versus AB controls) from thermoneutral (27°C) to hot (35°C) environments.

Inclusion criteria

• Between 18 and 65 years of age;
• Duration of injury ≥ 1 year;
• Level of SCI C4-T1;
• Euhydration (Subjects will be instructed to avoid caffeine and alcohol, maintain normal salt and water intake, and avoid strenuous exercise for 24 hours prior to study); and
• Age (± 5 years) and gender matched AB control group.

Exclusion criteria

• Known heart and/or blood vessel disease;
• High blood pressure;
• Kidney disease;
• Diabetes mellitus;
• Acute illness or infection;
• Dehydration;
• Pregnant women;
• Untreated thyroid disease, and
• Broken, inflamed, or otherwise fragile skin.