Body Parameters as an Independent Predictor of Acute Pancreatitis

This study is to assess the predictive significance of visceral adipose tissue (VAT) and visceral adipose tissue /skeletal muscle tissue ratio (VAT/SMT ratio) for the prognosis in acute pancreatitis (AP) patients.

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Key information

Conditions

Acute Pancreatitis Digestive System Diseases Pancreatic Diseases Pancreatitis

Age range

18 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Ningbo NO.1 hospital

Ningbo, Zhejiang, 315010, China

About this study

Acute pancreatitis (AP) is a sudden inflammation of the pancreas. However, one-fifth of patients may develop severe complications with a mortality between 10%-20% It remains a difficulty to find an effective method for prediction of severity of AP at early stage.

It is well-established that obesity (defined as body mass index[BMI]>30kg/m2 by the World Health Organization) is a risk factor for AP and increases the incidence of systemic complication, motality. There are a lot of parameters related to saropenic obesity, including areas of visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), skeletal muscle tissue (SMT), and VAT/SMT ratio. it is unclear which parameter is the best predictor of severe AP. Thus, this study is aimed to investigate the association between these parameters and AP severity and find the best predictor of AP.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

diagnosed with AP
age >18 years

Exclusion criteria

age<18years
missing data in the electronic medical record
history of AP

Treatment and study plan

Primary outcomes

Comparisons of variables according to AP severity

Time frame: the physical examination data in the year of 2017

Comparisons of variables according to AP severity by one-way analysis of variance (ANOVA) and Likelihood Ratio
Relationships between VAT and severity outcomes Relationships between VAT and severity outcomes Relationships between VAT and severity outcomes Relationships between body parameters and severity outcomes

Time frame: the physical examination data in the year of 2017

Relationships between VAT and severity outcomes by Likelihood Ratio

Sponsors and collaborators

Lead sponsor

Ningbo No. 1 Hospital

Other

Registry information

Official study title

Body Parameters as an Independent Predictor of Acute Pancreatitis: A Propensity Score-matched Case-control Study

Important dates

Study start: 2017
Primary completion: 2018
Study completion: 2018
First posted: Mar 29, 2018
Registry last updated: Mar 29, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed