Hacettepe University
Ankara, Altındağ, Turkey (Türkiye)
Location status: Recruiting
Recruiting
NCT Number: NCT07151534
Body Awareness, Trunk Stability, and Arm Function in MS
The aim of this study is to investigate the relationship between body awareness, trunk stabilization, and upper extremity functionality in patients with Multiple Sclerosis (MS).
Hypotheses of the study:
H1: There is a significant relationship between body awareness and upper extremity functionality in patients with MS.
H2: There is a significant relationship between body awareness and trunk stabilization in patients with MS.
H3: Body awareness is reduced in patients with MS compared to healthy individuals.
H4: Trunk stabilization is reduced in patients with MS compared to healthy individuals.
H5: Upper extremity functionality is reduced in patients with MS compared to healthy individuals.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
10 year and older
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
Patients' demographic and disease-specific information will be recorded. Subsequently, body awareness, upper extremity functionality, and trunk stabilization will be assessed.
Who can participate
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- Diagnosed with Multiple Sclerosis (MS) by a neurologist according to the McDonald criteria
- Aged 18 years or older
- Expanded Disability Status Scale (EDSS) score ≤ 5
- Mini-Mental State Examination (MMSE) score ≥ 24
- A control group consisting of healthy individuals matched with MS patients in terms of age and sex
Exclusion criteria
- Having a neurological disorder other than MS
- Having experienced a relapse and/or used corticosteroids in the past 3 months
- Having an orthopedic/systemic condition affecting the upper extremities or trunk
- Being pregnant
- Refusing to participate or not providing written informed consent
- Healthy individuals who have an orthopedic/systemic condition affecting the upper extremities or trunk, who are pregnant, or who do not agree to participate and provide written informed consent will be excluded.
Treatment and study plan
Primary outcomes
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Body Awareness Questionnaire
Time frame: up to 6 months
To assess body awareness, the Body Awareness Questionnaire will be used.This questionnaire consists of 18 items, each scored on a scale from 1 to 7, and evaluates body awareness. Higher scores indicate better body awareness. The Turkish version has been validated and found to be reliable.
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Body Awareness Rating Questionnaire
Time frame: up to 6 months
To assess body awareness,the Body Awareness Rating Questionnaire will be used. Body Awareness Rating Questionnaire:This questionnaire includes 24 items across 4 domains: function, mood, feeling/sensation, and awareness. Higher scores indicate better body awareness. The Turkish version has been validated and shown to be reliable.
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Upper Extremity Functionality-Grip strength
Time frame: up to 6 months
Grip strength will be measured with a Jamar dynamometer. It will be performed three times bilaterally, and average values (kg) will be recorded.
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Upper Extremity Functionality-Pinch strength
Time frame: up to 6 months
Pinch strengths will be assessed using a Baseline pinch gauge. It will be performed three times bilaterally, and average values (kg) will be recorded.
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Upper Extremity Functionality-Nine Hole Peg Test (9HPT)
Time frame: up to 6 months
The 9HPT will evaluate hand dexterity by timing how quickly participants place and remove nine pegs. Each hand will be tested three times. It will be recorded in seconds. An average time ≥33.3 seconds will indicate dysfunction in MS patients.
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Trunk Stabilization- Trunk Impairment Scale (TIS),
Time frame: up to 6 months
Trunk stabilization will be evaluated using the TIS.TIS: Assesses static/dynamic balance and trunk coordination (17 items, 0-23 points).
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Trunk Stabilization-plank endurance test
Time frame: up to 6 months
Trunk stabilization will be evaluated using the plank endurance test. The test measures core endurance. Plank test: Time held in forearm plank recorded. It will be recorded in seconds.
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Trunk Stabilization-side bridge test
Time frame: up to 6 months
Trunk stabilization will be evaluated using the side bridge test. The test measures core endurance Time held in side plank on both sides recorded.It will be recorded in seconds.
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Trunk Stabilization-Modified Biering-Sorensen
Time frame: up to 6 months
Trunk stabilization will be evaluated using the Modified Biering-Sorensen test. The test measures core endurance. Time holding trunk in horizontal position prone over table edge. It will be recorded in seconds.
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Trunk Stabilization-Trunk flexor test
Time frame: up to 6 months
Trunk stabilization will be evaluated using the Trunk flexor test test.The test measures core endurance. Time maintaining 60° trunk flexion with knees/hips at 90°. It will be recorded in seconds.
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Trunk Stabilization-Sit up test
Time frame: up to 6 months
The 30-second Sit-up Test measures core strength. The person lies on their back with knees bent and feet on the floor. They do as many sit-ups as possible in 30 seconds, keeping proper form. The score is the number of correct sit-ups completed.
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Trunk Stabilization-Modifiye push up test
Time frame: up to 6 months
The 30-second Modified Push-up Test measures core strength. The person starts in a push-up position but with knees on the floor. They perform as many push-ups as possible in 30 seconds, keeping the body straight and lowering the chest close to the ground. The score is the number of correct push-ups completed.
Study contacts
Contact information is provided by the study sponsor or research team.
Sponsors and collaborators
Lead sponsor
Hacettepe University
Other
Registry information
Official study title
Investigation of the Relationship Between Body Awareness, Trunk Stabilization, and Upper Extremity Functionality in Individuals With Multiple Sclerosis
Important dates
- Study start
- 2025
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Sep 3, 2025
- Registry last updated
- May 22, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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