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OpenTrials
Completed

NCT Number: NCT03200314

Blood Recirculation and vvECMO

A prospective, observational study will be performed measuring recirculation of blood through a veno-venous Extracoporeal Membrane Oxygenation (vvECMO) in patients with acute respiratory distress syndrome (ARDS) on vvECMO. ECMO blood flow will be adjusted with respect to recirculation.

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Key information

Conditions

ARDS Extracorporeal Membrane Oxygenation

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Charite University, Berlin, Germany

Berlin, 13353, Germany

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients aged 18 years or older
  • ARDS
  • veno-venous ECMO

Exclusion criteria

  • age < 18 years
  • hemodynamic instability during measurement of recirculation
  • pregnancy
  • inability to obtain patient's consent or consent of legal guardian

Treatment and study plan

Measurment of blood recirculation

Other

Ultrasound based measurments of blood recirculating through the vvECMO circuit.

Primary outcomes

  1. Recirculation of vvECMO blood flow

    Time frame: Once within first week after ICU admission during 4 hours

    Amount of ECMO blood flow recirculating through the vvECMO circuit

Secondary outcomes

  1. Reduction of vvECMO blood flow

    Time frame: Once within first week after ICU admission during 4 hours

    Reduction of vvECMO blood flow if a significant recirculation can be measured

  2. Arterial blood oxygen content after reduction of vvECMO blood flow

    Time frame: Once within first week after ICU admission during 4 hours

    Change in arterial blood oygen content after reduction of vvECMO blood flow

Sponsors and collaborators

Lead sponsor

Charite University, Berlin, Germany

Other

Registry information

Official study title

Measurment of Blood Recirculation and Adjustment of vvECMO Blood Flow During Veno-venous Extracoporeal Membrane Oxygenation

Important dates

Study start
2017
Primary completion
2018
Study completion
2018
First posted
Jun 27, 2017
Registry last updated
Jun 26, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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