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Completed

NCT Number: NCT03847012

Blood Pressure Responses to Different Exercise Modes in Coronary Artery Disease

The purposes of this study were to compare blood pressure responses of the same target heart rate on different exercise modes in patients with coronary artery diseases (CAD) and to compare the effects of blood pressure responses after exercise training.

The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. The subjects performed the treadmill or stationary bicycle exercise randomly.

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Key information

Age range

20 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

National Taiwan University Hospital

Taipei, 100, Taiwan

About this study

Considering cardiopulmonary rehabilitation intensity is often setting by heart rate clinically, and only few study focused on exercise responses patients with CAD, the purposes of this study were to compare blood pressure responses of the same target heart rate on different exercise modes in patients with CAD and to compare the effects of blood pressure responses after exercise training.

This is a crossover trial study. The investigators will recruit 30 subjects with CAD who are referred to phase II cardiopulmonary rehabilitation exercise training. After at least 3 times of familiar with the cardiopulmonary rehabilitation training machine, the subjects performed the treadmill or stationary bicycle and exercise to personalized target heart rate for 10 minutes, take a rest until the heart rate recover to the resting heart rate, and then repeated the exercise in another exercise mode. The test order will be random. After at least 12 times of cardiopulmonary rehabilitation training, the test will be performed again.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with coronary artery diseases who are referred to phase II cardiopulmonary rehabilitation exercise training.

Exclusion criteria

  • patients with non-coronary artery diseases
  • atrial fibrillation
  • neurological or musculoskeletal problems

Treatment and study plan

Exercise

Other

The test order will be random. After at least 12 times of cardiopulmonary rehabilitation training, the test will be performed again.

Primary outcomes

  1. heart rate

    Time frame: Change from baseline heart rate at 6 weeks

    heart rate

  2. blood pressure

    Time frame: Change from baseline blood pressure at 6 weeks

    blood pressure

Secondary outcomes

  1. perceived exertion scale

    Time frame: baseline and 6 weeks

    how effort the participant feel. Range from 1to 10. Higher values represent harder.

  2. heart rate variability

    Time frame: baseline and 6 weeks

    heart rate variability

Other outcomes

  1. age

    Time frame: baseline

    questionnaire

  2. gender

    Time frame: baseline

    questionnaire

  3. risk level of exercise

    Time frame: baseline

    AACVPR Stratification Algorithm for Risk of Event. Include high, moderate and low risk

  4. co-morbidity

    Time frame: baseline

    questionnaire

  5. medication

    Time frame: baseline

    questionnaire

  6. level of exercise intensity

    Time frame: baseline

    percent of heart rate reserve

Sponsors and collaborators

Lead sponsor

National Taiwan University Hospital

Other

Registry information

Official study title

The Blood Pressure Responses to Different Exercise Models in Patients With Coronary Artery Disease

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Feb 20, 2019
Registry last updated
Apr 8, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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