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OpenTrials
Completed

NCT Number: NCT05674097

Blood Flow Path Reconstruction in Rectal Cancer

A total of 89 patients with distal sigmoid and rectal cancer were referred for observation and underwent MS-CTA between June 2020 and March 2022. The distribution of the left colic artery (LCA) was classified, and the presence of the accessory middle colic artery (AMCA) was assessed. Blood flow paths were planned preoperatively based on the classification of LCA branches. High ligation was performed during standard radical surgery. Intraoperatively, particular care was taken to preserve the bifurcation of the ascending and descending branches of the LCA. The planned blood flow paths were then compared with the actual postoperative blood flow paths to validate the previously proposed mechanism.

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Key information

Age range

39 year–81 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Guoqin LIU

Jinan, Shandong, 250013, China

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Clinical diagnosis of distal sigmoid colon or rectal cancer
  • cTNM stage confirmed as I-III on MRI or CT
  • Undergoing laparoscopic anterior resection (LAR)

Exclusion criteria

  • Arterial phase scanning initiated too early
  • Unclear anatomic structure on imaging
  • No postoperative enhanced CT

Treatment and study plan

No intervention

Other

no intervention

Primary outcomes

  1. Six pattens of blood flow and AMCA based on the preoperative observation

    Time frame: 1 hour after the manual subtraction computed tomography angiography (MS-CTA) procedure

Sponsors and collaborators

Lead sponsor

Shandong First Medical University

Other

Collaborators

  • Jinan Central Hospital

Registry information

Official study title

Blood Flow Path Reconstruction in Rectal Cancer After High IMA Ligation Through Preoperative and Postoperative Comparison by Manual Subtraction CTA

Important dates

Study start
2020
Primary completion
2022
Study completion
2022
First posted
Jan 6, 2023
Registry last updated
Sep 22, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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