Blood Flow Change After Free Flap Surgery in Diabetic Patients

We aim to evaluate the flow change of arterial anastomosis site during free flap surgery in diabetic patients.

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Key information

Conditions

Diabetes Diabetes Mellitus Endocrine System Diseases Glucose Metabolism Disorders Metabolic Diseases Nutritional and Metabolic Diseases

Age range

18 year–79 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Asan Medical Center

Seoul, 05505, South Korea

About this study

Objective: flow change of arterial anastomosis site during free flap surgery in diabetic patients.

Background: No research was published about flow change of arterial anastomosis site of the free flap during surgery.

Plan: Using Duplex sonography, various parameters related flap perfusion will be evaluated before and after the administration of alprostadil.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Plan to receive free flap transfer under general anesthesia
Age: >=18 and <80 years old
History of diabetes mellitus
Administration of alprostadil during surgery
Volunteer, who are provided written informed consent prior to study participation

Exclusion criteria

Refuse the participation of study
>= American society of anesthesiologist physical status IV
Use of any vasopressor or inotropic for hemodynamic instability before participation of study
Inappropriate subjects who are identified by researchers

Treatment and study plan

Alprostadil

Drug

Vasodilator for anastomosis-site of free flap

Other names: Eglandin

Primary outcomes

Flow change

Time frame: before alprostadil administration, 30 mins after alprostadil administration

Peak velocity of anastomosis-site of free flap

Sponsors and collaborators

Lead sponsor

Asan Medical Center

Other

Registry information

Official study title

Prospective Observational Study of the Changes of Blood Flow of Arterial Anastomosis-site of Free Flap in Diabetic Patients Who Undergoing Free Flap Transfer

Important dates

Study start: 2017
Primary completion: 2018
Study completion: 2018
First posted: Jan 23, 2017
Registry last updated: Nov 30, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed