Skip to main content
OpenTrials
Completed

NCT Number: NCT05213130

Blood Donation and Subjective Well-being

This study investigates the psychological effects of blood donation among adult donors at the Guangzhou Blood Center. The primary objective is to examine whether a brief gratitude-based intervention delivered after donation enhances donors' subjective well-being (SWB) and basic psychological need (BPN) satisfaction. Participants who complete a whole-blood donation are randomly assigned to either an Intervention group, receiving a standardized gratitude reinforcement message accompanied by a vignette emphasizing the life-saving impact of donation, or a Control group that receives no additional message. All participants complete questionnaires at Time 1 (immediately after donation) and at Time 2 (4-22 days later), assessing SWB and related psychosocial variables.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Blood Donation Happiness

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Guangzhou Blood Center

Guangzhou, Guangdong, 510095, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Successfully completed a whole-blood donation at the Guangzhou Blood Center during the study period.
  • Able to read and understand the study materials and provide informed consent.
  • Provided the correct answer to a control question in the questionnaire
  • Provided their phone number.
  • Donated blood was successfully supplied to the hospitals.

Exclusion criteria

  • Whole blood donors with positive or suspicious serological results.

Treatment and study plan

Information

Other

A reminder to inform donors that their blood has saved patient's life in a questionnaire.

Primary outcomes

  1. Score of Subjective Well-Being at Time 2

    Time frame: 4-22 days after donation

    Subjective well-being (SWB) is assessed at follow-up using a validated multi-item measure capturing life satisfaction and affective well-being.

    Affect-Adjective Scale (validated Chinese version): 9 items, each scored 1-7. Satisfaction with Life Scale (validated Chinese version): 5 items scored 1-7. An aggregate SWB score was calculated by standardizing and summing life satisfaction scores with positive affect scores and subtracting the negative affect score from them.

    Scores range from low to high levels of well-being. The primary objective is to evaluate whether exposure to the gratitude-based intervention leads to higher SWB relative to the control condition.

Secondary outcomes

  1. Score of Subjective Well-being at Time 1

    Time frame: Immediately after donation

    Baseline Subjective well-being (SWB) is measured using a validated multi-item measure capturing life satisfaction and affective well-being.

    Affect-Adjective Scale (validated Chinese version): 9 items, each scored 1-7. Satisfaction with Life Scale (validated Chinese version): 5 items scored 1-7. An aggregate SWB score was calculated by standardizing and summing life satisfaction scores with positive affect scores and subtracting the negative affect score from them.

    Scores range from low to high levels of well-being.

  2. Score of Basic Psychological Needs Satisfaction at Time 1

    Time frame: Immediately after donation

    Baseline basic psychological needs (BPN) satisfaction is measured using a 9-item Basic Psychological Needs Scale (validated Chinese version). The scale contains subscales for autonomy, competence, and relatedness, using a 7-point scale ranging from 1 (not at all true) to 7 (very much true). Each of the three subscales was averaged to form an index of general BPN satisfaction. This measure captures donors' immediate psychological experience following donation. Higher scores indicate greater psychological need satisfaction.

  3. Score of Basic Psychological Needs Satisfaction at Time 2

    Time frame: 4-22 days after donation

    The same basic psychological needs satisfaction (BPN) scale is administered at follow-up to examine changes after the intervention. It is measured using a 9-item Basic Psychological Needs Scale (validated Chinese version). The scale contains subscales for autonomy, competence, and relatedness, using a 7-point scale ranging from 1 (not at all true) to 7 (very much true). Each of the three subscales was averaged to form an index of general BPN satisfaction. Higher scores indicate greater psychological need satisfaction.

  4. Score of Blood Donation Intention at Time 1

    Time frame: Immediately after donation

    Intention to donate blood again in the future at Time 1 is measured using a single self-report intention item rated from 1 (very unlikely) to 7 (very likely), with higher scores indicating stronger intention to donate. The same item is administered at Time 1 and Time 2 to assess changes over time and to examine potential effects of the intervention on future donation motivation.

  5. Score of Blood Donation Intention Score at Time 2

    Time frame: 4-22 days after donation

    Intention to donate blood again in the future at Time 2 is measured using a single self-report intention item rated from 1 (very unlikely) to 7 (very likely), with higher scores indicating stronger intention to donate. The same item is administered at Time 1 and Time 2 to assess changes over time and to examine potential effects of the intervention on future donation motivation.

  6. Re-Donation Rate within One Year

    Time frame: Up to 12 months after the initial donation

    Actual re-donation rate is obtained from the Guangzhou Blood Centre's donation records. The variable indicates whether the participant returned for another whole-blood or component donation within one year.

Sponsors and collaborators

Lead sponsor

Guangzhou Blood Center

Other Gov

Registry information

Official study title

The Relationship Between Blood Donation and Subjective Well-being

Important dates

Study start
2022
Primary completion
2022
Study completion
2022
First posted
Jan 28, 2022
Registry last updated
Jan 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.