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NCT Number: NCT07626372

Bite Force and Occlusal Force Distribution Following Root Canal Treatment.

Understanding the changes in bite force and occlusal force distribution in ETT is clinically important, as it can directly influence tooth prognosis, guide restorative treatment planning, and impact the long-term survival of the treated tooth. Therefore, this study aims to further explore changes and possible correlation in maximum bite force (MBF), occlusal force distribution and patients' subjective perception of chewing function of endodontically treated teeth after non-surgical root canal treatment, subsequent restoration, and during long-term follow-up, along with comparing to contralateral vital teeth.

Methods: Patients aged 20-60 years who underwent non-surgical root canal treatment at the Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn University, with the following teeth indicated for endodontic treatment. Measurements of maximum bite force (MBF) of ETT and contralateral vital teeth, relative occlusal force (ROF), and questionnaire responses, are performed at the following time points: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

Differences in MBF and ROF over time points within subjects and differences in MBF and ROF between ETT and their contralateral vital teeth were statistically analyzed.

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Key information

Conditions

Endodontically Treated Teeth Dental Pulp Diseases Stomatognathic Diseases Tooth Diseases Tooth, Nonvital

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Graduate Endodontic Clinic, Faculty of Dentistry, Chulalongkorn university

Bangkok, 10330, Thailand

Location contact

Prom Wongmaneerojn

PRINCIPAL_INVESTIGATOR

Thanomsuk Jearanaiphaisarn

CONTACT

[email protected]

6622188795

Uraiwan Chokechanachaisakul

CONTACT

[email protected]

6622188795

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Premolars or molars diagnosed with pulp necrosis or previously initiate therapy with normal apical tissues, asymptomatic apical periodontitis, or chronic apical abscess without full coverage restoration.
Adequate remaining tooth structure for cuspal coverage restoration.
Presence of adjacent teeth and functional opposing natural teeth.
No analgesics drug effect at the time of investigation or not have taken analgesics 6 hours ago.

Exclusion criteria

Patients undergoing other dental treatments during the study period that may interfere with occlusion or bite force distribution, such as orthodontic treatment, jaw surgery, or full mouth restoration.
Received treatments that cause weakness of the jaw and facial muscles, such as botox injections.
History or symptoms of temporomandibular disorders (TMD)
Periodontal disease with second- or third-degree mobility
Teeth presenting crack lines extending into the pulp chamber floor or root canal orifices.

Treatment and study plan

Primary outcomes

Maximum bite force

Time frame: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

Maximum bite force of the endodontically treated tooth and its contralateral tooth in each patient will be measured using the FlexiForce ELF System and FlexiForce B201 sensor.
Relative occlusal force

Time frame: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

Relative Occlusal Force are measured with the T-Scan III system. A device will be inserted into the mouth of the patients, and they are instructed to bite firmly three times at the maximum cusp intersection position.

Secondary outcomes

Patients' subjective perception of chewing function

Time frame: before NS-RCT, 1 month after completion of NS-RCT (before doing restoration), 3 months after crown restoration, 1, 2 and 4 years after completion of NS-RCT.

A questionnaire will be used to assess patients' subjective perceptions of chewing function, including preferred chewing side, frequency of hard food consumption, and parafunctional habits such as bruxism and clenching.

Study contacts

Contact information is provided by the study sponsor or research team.

Thanomsuk Jearanaiphaisarn

CONTACT

[email protected]

6622188795

Sponsors and collaborators

Lead sponsor

Chulalongkorn University

Other

Registry information

Official study title

Changes in Bite Force and Occlusal Force Distribution Following Root Canal Treatment, Restoration, and Over Time: A Prospective Observational Study

Acronym: B-FORCE RCT

Important dates

Study start: 2026
Primary completion: 2027
Study completion: 2030
First posted: Jun 4, 2026
Registry last updated: Jun 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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