Birth Cohort Study for Respiratory Infections

Inclusion criteria

• Age: 18-35 years
• Parity: any but with history of previous normal delivery
• Weight: Body Mass Index greater than 18.5 but less than 35
• Past obstetric history: Uncomplicated pregnancy, unremarkable medical and obstetric conditions
• Current pregnancy: Uneventful progression of pregnancy
• General health: Normal health related functional status during pregnancy
• Singleton pregnancy as determined by clinical examination and/or by ultrasonography
• Cephalic presentation as determined by abdominal clinical examination
• Expected to have normal pregnancy related outcome
• Written informed consent

Exclusion criteria

• Medical history: Known history of diabetes, hypertension, or any systemic disorder
• Gynecological history: History of major gynecological problem/treatment
• Complications in previous pregnancy
• Previous obstetric cholestasis
• Previous acute fatty liver disease
• Conditions during current pregnancy

• RhD negative mother
• APH/Placental abruption
• Placenta Praevia
• Unstable lie
• Multiple pregnancy
• Pregnancy induced hypertension (systolic > 140 mm of Hg, diastolic > 90 mm of Hg)
• Severe pre-eclampsia or eclampsia
• Gestational diabetes
• Onstetric cholestasis
• Current history of drug/alcohol abuse
• BMI of less than 18.5 or more than 35. Severe pallor as detected clinically or by HB level (< 7 gm/dL), and oedema
• Blood samples drawn and tested for VDRL (Positive VDRL) Cephalopelvic disproportion (CPD)
• History of taking antibiotic within 3 weeks prior to this study
• Patient unwilling to comply with study protocol