Biorepository to Support Research in Kidney Diseases

To support advances in the understanding of pathophysiology and therapies of kidney diseases by creating a BioBank of kidney tissue, DNA, plasma, and urine from patients with kidney diseases.

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Key information

Conditions

Acute Kidney Injury Acute Interstitial Nephritis Acute Tubulointerstitial Nephritis Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Kidney Diseases Male Urogenital Diseases Renal Insufficiency Urogenital Diseases Urologic Diseases

Age range

18 year–99 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Yale New Haven Hospital Saint Raphael Campus, New Haven, Connecticut, United States

About this study

A biorepository of human samples to support research to advance understanding of human kidney diseases will be created. Clinically, kidney diseases are detected by blood and urine laboratory tests. However, the underlying cause of kidney disease is often not clear on blood and urine tests. In such cases, a clinician may choose to perform a kidney biopsy to establish the diagnosis. Patients who are scheduled to undergo a kidney biopsy will be invited to participate in this proposed study.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients scheduled to undergo a clinically indicated kidney biopsy
English or Spanish speaking

Exclusion criteria

Under 18 years or age
Known pregnancy
Additional vulnerable individuals (incarcerated, institutionalized, or otherwise unable to participate in the study)
Inability to provide informed consent

Treatment and study plan

Primary outcomes

Histological diagnosis

Time frame: 5 years

Histological diagnosis of kidney disease determined by evaluation by renal pathologists

Secondary outcomes

Occurrence of chronic kidney disease, end stage kidney disease or death

Time frame: 10 years

Track outcomes in participants recruited for up to 10 years

Sponsors and collaborators

Lead sponsor

Yale University

Other

Collaborators

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Registry information

Important dates

Study start: 2020
Primary completion: 2030
Study completion: 2035
First posted: Apr 13, 2020
Registry last updated: Aug 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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