Biometrical Evaluation of the Efficacy of a Food Supplement Versus Placebo

Inclusion criteria

• Phototype: I to IV;
• Subjects with normal to dry skin;
• Subjects with healthy skin on the study area;
• Non-smokers;
• Has normal nutritional habits (not vegetarian/vegan);
• Is not pregnant or lactating;
• Has a BMI of 18 - 33 kg/m2;
• Is willing to refrain from taking dietary supplements (at best not at all, in any case not during the last month before study start);
• Willing not to use any oral products or any nutritional supplementation aiming at improving skin status during the course of the study;
• No history of malabsorption diseases, liver diseases, or diseases of the lipid metabolism;
• Uses no medication, which may interact with the study product

Exclusion criteria

• For women: pregnant or nursing woman or woman planning to get pregnant during the study;
• Cutaneous pathology on the study zone (eczema, etc.);
• Subject with make-up on the day of the visit at the laboratory;
• Use of topical or systemic treatment during the previous weeks liable to interfere with the assessment of the efficacy of the study product:

• change in anti-wrinkle, smoothing and/or firming topical products within previous week on the studied zones,
• non-invasive procedures within previous month on the studied zones,
• intake of food supplement acting on skin within the three previous months,
• invasive procedures:

• deep chemical peeling within previous 3 months on the studied zones,
• mesotherapy, dermapen, laser within previous 6 months on the studied zones,
• botox and/or hyaluronic acid injections within previous 12 months on the studied zones;
• Intake of vitamin substances and diets comprising a change of normal eating habits;
• Known allergy to one or several investigational product´s ingredients;
• Participation in a nutritional study within the last 30 days;
• Surgical or internal diseases e.g. a metabolic or endocrine disease that may affect the outcome of the study (e.g. diabetes, liver diseases, kidney disorders) or having a history of medical or surgical events that may significantly affect the study outcome including any cardiovascular disease, skin disease, hypertension (>140/90 mm Hg in three repeated measurements).