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OpenTrials
Completed

NCT Number: NCT04963023

Biomarkers of Chronic Obstructive Pulmonary Disease

There are few studies about immunological explorations in COPD. Because of the complications of lung biopsies, analyses are generally made on blood samples instead of lung tissue. No study tried to classify COPD vs Asthma vs ACOS. The investigators wondered if there were differences in biomarkers between these groups. The investigators decided to open a pilot-study among COPD patients followed in Amiens-University Hospital. Each patient will be examined and a blood-test will be performed.

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Key information

Conditions

COPD Asthma Asthma-COPD Overlap Syndrome Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome Bronchial Diseases Chronic Disease Disease Attributes Hypersensitivity Hypersensitivity, Immediate Immune System Diseases Lung Diseases Lung Diseases, Obstructive Pathologic Processes Pathological Conditions, Signs and Symptoms Pulmonary Disease, Chronic Obstructive Respiratory Hypersensitivity Respiratory Tract Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHU Amiens

Amiens, 80480, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • BPCO patients
  • ACOS patients
  • asthmatic patient without BPCO

Exclusion criteria

  • infection
  • exacerbation
  • immunosuppressive treatment
  • immunosuppressive disease

Treatment and study plan

Physical examinations

Other

BPCO physical examinations

Blood test

Diagnostic Test

blood test in order to study immunologic markers

Primary outcomes

  1. identification specific blood immunologic marker for COPD

    Time frame: one hour

    COPD biomarkers are blood immunologic markers

Secondary outcomes

  1. Complete blood count (CBC) Variation between COPD and asthmatic patients

    Time frame: one hour

  2. c-reactive protein concentration variation between COPD and asthmatic patients

    Time frame: one hour

  3. Plasma protein electrophoresis profile Variation between COPD and asthmatic patients

    Time frame: one hour

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Registry information

Official study title

Specific Biomarker Identification of Different Subgroups of Chronic Obstructive Pulmonary Disease

Acronym: BIOBPCO

Important dates

Study start
2021
Primary completion
2023
Study completion
2023
First posted
Jul 15, 2021
Registry last updated
Aug 23, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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