Skip to main content
OpenTrials
Completed

NCT Number: NCT03388333

Biomarkers in Patients Undergoing Atrial Fibrillation Ablation

The investigators aim to find biomarkers to determine the success of pulmonary vein isolation for the treatment of atrial fibrillation.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Atrial Fibrillation Arrhythmias, Cardiac Cardiovascular Diseases Heart Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Department of Cardiology - Electrophysiology, University Heart Centre, University Hospital Hamburg-Eppendorf

Hamburg, 20246, Germany

About this study

The investigators perform an observational study in patients undergoing pulmonary vein ablation to treat atrial fibrillation. Additionally, electrophysiological procedures not related to pulmonary vein isolation are also followed. The aim of the study is finding biomarkers that are able to predict short-term outcome of the procedure.The primary endpoint is defined as reoccurrences of atrial fibrillation within the first three months after pulmonary vein isolation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • patients with atrial fibrillation scheduled for pulmonary vein isolation with either radiofrequency of cryoballoon
  • patients scheduled for an electrophysiological study without ablation
  • patients with a catheter ablation at the cavotricuspid isthmus for the treatment of right atrial flutter

Exclusion criteria

  • patients with concurrent pulmonary vein isolation and ablation of the cavotricuspid isthmus
  • Acute myocardial infarction, coronary artery bypass graft surgery or open heart surgery within less than 3 months prior to inclusion

Treatment and study plan

Catheter ablation

Procedure

Primary outcomes

  1. Number of patients with short term reoccurrences of atrial fibrillation after ablation.

    Time frame: 3 months

    Holter ECGs and ECGs after atrial fibrillation ablation

Secondary outcomes

  1. Change in heart rate after pulmonary vein isolation

    Time frame: 3 days.

    Heart rates are recorded at admission and release from the hospital.

Sponsors and collaborators

Lead sponsor

Universitätsklinikum Hamburg-Eppendorf

Other

Registry information

Official study title

A Single-center Observational Study to Find Biomarkers for the Outcome of Catheter Ablation in Patients With Atrial Fibrillation

Important dates

Study start
2017
Primary completion
2018
Study completion
2019
First posted
Jan 2, 2018
Registry last updated
Jun 7, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.