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NCT Number: NCT07307326

Biomarker Feedback Intervention

The goal of the study is to examine alcohol use behaviors of young adults through the use of testing the feasibility of adding an innovative brief personalized alcohol biomarker feedback component (TAC feedback) to an existing efficacious personalized feedback intervention, eCHECKUP TO GO (eCTG), and how (if at all) the intervention impacts drinking behaviors in high-risk college students. The study will conduct a feasibility assessment of the TAC feedback component, and will also assess the effects of the eCTG + TAC at 6-months post-baseline relative to an eCTG only group.

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Key information

Conditions

High Risk Drinking Alcohol Drinking Alcohol Drinking in College Behavior College Student Drinking Drinking Behavior

Age range

18 year–23 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Between the ages of 18-23 at enrollment
  • Endorse drinking 4+/5+ (women/men) on a typical Friday or Saturday in the past 3-months
  • Report at least 1 alcohol-induced blackout in the past 3-months
  • Willing to wear a TAC sensor for 14 days at Waves 1 and 2

Exclusion criteria

  • Younger than 18 at baseline
  • Not fluent in English
  • No Internet access

Treatment and study plan

eCHECKUP TO GO (eCTG)

Behavioral

A brief, web-based program designed by San Diego State University to reduce high-risk drinking by providing personalized normative feedback regarding alcohol use, risk factors, and risks associated with drinking and accurate information about alcohol

eCHECKUPTOGO + brief personalized alcohol biomarker feedback intervention (eCTG + TAC)

Behavioral

Participants will receive the eCHECKUPTOGO in addition to the transdermal alcohol concentration (TAC) personalized feedback. The TAC is a brief individually delivered intervention based on the principles of Motivational Interviewing and focuses on increasing students' motivation to reduce harmful drinking by drinking in a safer, less risky manner. Participants will receive information on their drinking (both from the TAC sensor and daily diary data). Participants will be asked about drinking events during the past 2 weeks (how reflective they were of typical patterns and if a night stood out as particularly negative). Students will receive information and visual representations about TAC rise rates and peaks, and then be shown how their drinking during the past 2 weeks maps onto those visuals.

Primary outcomes

  1. Examine changes in Transdermal Alcohol Concentration (TAC) rise rate

    Time frame: Baseline, 6 months

    TAC rise rate will be collected via the BACtrack Skyn wrist sensor, which measures transdermal alcohol concentration (TAC) in micrograms of ethanol per liter of air every 20 seconds to obtain biomarkers - rise rate is a TAC increase.

  2. Examine changes in Transdermal Alcohol Concentration (TAC) peak intoxication level

    Time frame: Baseline, 6 months

    TAC peak will be collected via the BACtrack Skyn wrist sensor, which measures transdermal alcohol concentration (TAC) in micrograms of ethanol per liter of air every 20 seconds to obtain biomarkers - peak is the maximum TAC recorded per day.

  3. Examine high risk drinking days

    Time frame: Baseline, 6 months

    Heavy episodic drinking (HED) days are recorded when women indicate drinking 4+ drinks in 2 hour window/men indicate drinking 5+ drinks in 2 hour window. High-intensity drinking (HID) days are recorded when women indicate drinking 8+ drinks in 2 hour window/men indicate drinking 10+ drinks in 2 hour window.

Secondary outcomes

  1. Examine negative consequences of alcohol use

    Time frame: Baseline, 6 months

    Alcohol related consequences (e.g., said or done embarrassing things) from the past 3 months will be measured using the established Brief Young Adult Alcohol Consequences Questionnaire. Response options will be on a 5-point scale ranging from (0) No or not in the past 3 months to (4) 4 or more times. Consequences will also be measures during the daily surveys on a Yes/No response scale.

  2. Examine Alcohol Use Disorder (AUD) symptoms

    Time frame: Baseline, 6 months

    Alcohol use disorder symptoms will be measured using the Alcohol Use Disorder Module of the SCID-5 and will be via in-person interview at baseline (past 12-months) and 6-month (past 6-months).

Study contacts

Contact information is provided by the study sponsor or research team.

Kimberly Mallett, PhD

CONTACT

[email protected]

814-441-6398

Rob Turrisi, PhD

CONTACT

[email protected]

814-865-7808

Sponsors and collaborators

Lead sponsor

Penn State University

Other

Registry information

Official study title

An Examination of the Feasibility of a Brief Personalized Alcohol Biomarker Feedback Intervention for High-risk College Students

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Dec 29, 2025
Registry last updated
Jul 8, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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