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OpenTrials
Completed

NCT Number: NCT02639780

Biochemical Alterations of Stored Erythrocyte Membranes

The investigators will define procoagulant properties of packed red blood cells and investigate whether packed red blood cells from certain donor populations are prone to induce procoagulant states.

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Key information

Conditions

Coagulation Cardiovascular Diseases Embolism and Thrombosis Thrombosis Vascular Diseases

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Medical University of Vienna

Vienna, 1090, Austria

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • group 1: healthy female volunteers 18-35 y.o.
  • group 2: healthy male volunteers 18-35 y.o.
  • group 3: healthy female volunteers 36-60 y.o.
  • group 4: healthy male volunteers 36-60 y.o.
  • group 5: female volunteers 36-60 y.o., BMI 26-45
  • group 6: male volunteers 36-60 y.o., BMI 26-45

Exclusion criteria

  • age below 18 years
  • age above 60 years

Treatment and study plan

protein expression pattern of packed red blood cells

Other

the proteome of packed red blood cells will be assessed at predefined time points

Primary outcomes

  1. protein expression pattern

    Time frame: week 0

  2. protein expression pattern

    Time frame: week 2

  3. protein expression pattern

    Time frame: week 4

  4. protein expression pattern

    Time frame: week 6

Sponsors and collaborators

Lead sponsor

Medical University of Vienna

Other

Collaborators

  • European Society of Anaesthesiology
  • Medical Scientific Fund of the Mayor of Vienna

Registry information

Important dates

Study start
2015
Primary completion
2019
Study completion
2021
First posted
Dec 24, 2015
Registry last updated
Jan 4, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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