Biobank For MS And Other Demyelinating Diseases

To establish a large, longitudinal collection of high quality samples and data from subjects with MS, selected other demyelinating diseases (Transverse Myelitis (TM), Neuromyelitis Optica (NMO) or Devic's, Acute Disseminated Encephalomyelitis (ADEM), and Optic Neuritis (ON)), and related and unrelated unaffected controls. Samples and data will be available as a shared resource to scientists researching the causes, sub-types, and biomarkers of MS and related demyelinating diseases.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Multiple Sclerosis Acute Disseminated Encephalomyelitis Autoimmune Diseases Autoimmune Diseases of the Nervous System Brain Diseases Central Nervous System Diseases Central Nervous System Infections Chronic Disease Cranial Nerve Diseases Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Disease Attributes Encephalomyelitis, Acute Disseminated Eye Diseases Immune System Diseases Infections Leukoencephalopathies Myelitis Myelitis, Transverse Neoplasms Neoplasms by Site Nervous System Diseases Nervous System Neoplasms Neurodegenerative Diseases Neuroinflammatory Diseases Neuromyelitis Optica Optic Nerve Diseases Optic Neuritis Paraneoplastic Syndromes Paraneoplastic Syndromes, Nervous System Pathologic Processes Pathological Conditions, Signs and Symptoms Post-Infectious Disorders Spinal Cord Diseases Transverse Myelitis

Sex eligibility

All sexes

Study type

Observational

Primary location

Barrow Neurological Institute, Phoenix, Arizona, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

age 18+ able to give informed consent or individuals younger than 18 with parental permission and able to give assent
willing to provide up to 110 ml (50 ml for < 18 years old) of blood via venipuncture
experienced at least one CNS demyelinating event characteristic of MS, TM, NMO, ADEM, or ON

Exclusion criteria

history of blood borne pathogens
allogeneic bone marrow transplant
clinical or radiological evidence of stroke, meningitis, or other well characterized diseases of the nervous system (with the exception of MS, TM, NMO, ADEM, or ON).
weight less than 37 pounds

Sponsors and collaborators

Lead sponsor

Accelerated Cure Project for Multiple Sclerosis

Other

Registry information

Official study title

Large-scale, Multi-disciplinary Sample and Data Repository for Multiple Sclerosis and Related Demyelinating Diseases

Important dates

Study start: 2006
Primary completion: 2030
Study completion: 2036
First posted: Mar 9, 2007
Registry last updated: Oct 2, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Recruiting